Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL6 | P41182 | 1/20 | 0.62 |
| ▸ | AURKA | O14965 | 6/20 | 0.54 |
| ▸ | CDK2 | P24941 | 4/20 | 0.54 |
| ▸ | GSK3B | P49841 | 4/20 | 0.54 |
| ▸ | FLT3 | P36888 | 3/20 | 0.54 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.54 |
| ▸ | STK17A | Q9UEE5 | 3/20 | 0.54 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.54 |
| ▸ | JAK2 | O60674 | 3/20 | 0.54 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.54 |
| ▸ | CDK1 | P06493 | 2/20 | 0.54 |
| ▸ | LYN | P07948 | 2/20 | 0.54 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.54 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.54 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.54 |
| ▸ | MARK3 | P27448 | 2/20 | 0.54 |
| ▸ | BLK | P51451 | 2/20 | 0.54 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.54 |
| ▸ | ERBB4 | Q15303 | 2/20 | 0.54 |
| ▸ | MARK2 | Q7KZI7 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL824411 | 0.86 | BCL6 (0.74) | BCL6AURKACDK2GSK3BFLT3 | |
| SCHEMBL9685913 | 0.79 | MEN1 (0.57) | AURKACDK2GSK3BFLT3CDK5 | |
| SCHEMBL27598771 | 0.79 | CDC7 (0.69) | BCL6AURKACDK2GSK3BFLT3 | |
| SCHEMBL5808094 | 0.78 | BCL6 (0.65) | BCL6AURKACDK2GSK3BFLT3 | |
| SCHEMBL19836613 | 0.77 | BCL6 (0.62) | BCL6AURKACDK2GSK3BFLT3 | |
| SCHEMBL5598234 | 0.77 | BCL6 (0.62) | BCL6AURKACDK2GSK3BFLT3 | |
| SCHEMBL5137042 | 0.77 | BCL6 (0.62) | BCL6AURKACDK2GSK3BFLT3 | |
| SCHEMBL4795724 | 0.77 | MAPT (0.66) | BCL6AURKACDK2GSK3BFLT3 | |
| Amanozine SCHEMBL689928 | 0.77 | BCL6 (1.00) | BCL6AURKACDK2PDPK1CDK1 | |
| Amanozine SCHEMBL30264199 | 0.77 | BCL6 (1.00) | BCL6AURKACDK2PDPK1CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0053743-B1 | REACTIVE DIOXAZINE DYESTUFFS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN DYEING AND PRINTING FIBROUS MATERIALS CONTAINING HYDROXYLE OR AMIDE GROUPS | BAYER AG (DE) | 1986-05-14 | — | — | EP | disclosed |
| US-4400504-A | DYEING AND PRINTING CELLULOSE AND POLYAMIDE AND-URETHANE FIBERS; TRIAZINE, PYRIDINE AND PYRIMIDINE DYES | BAYER AKTIENGESELLSCHAFT (DE) | 1983-08-23 | — | — | US | disclosed |
| EP-0053743-A2 | Reactive dioxazine dyestuffs, process for their preparation and their use in dyeing and printing fibrous materials containing hydroxyle or amide groups | BAYER AG (DE) | 1982-06-16 | — | — | EP | disclosed |