Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 5/20 | 0.69 |
| ▸ | CDK2 | P24941 | 5/20 | 0.69 |
| ▸ | FLT3 | P36888 | 4/20 | 0.69 |
| ▸ | GSK3B | P49841 | 4/20 | 0.69 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.69 |
| ▸ | STK17A | Q9UEE5 | 4/20 | 0.69 |
| ▸ | DAPK3 | O43293 | 3/20 | 0.69 |
| ▸ | PIM1 | P11309 | 3/20 | 0.69 |
| ▸ | CDK9 | P50750 | 3/20 | 0.69 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.69 |
| ▸ | MELK | Q14680 | 3/20 | 0.69 |
| ▸ | HIPK2 | Q9H2X6 | 3/20 | 0.69 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.69 |
| ▸ | JAK3 | P52333 | 3/20 | 0.69 |
| ▸ | MAP4K2 | Q12851 | 3/20 | 0.69 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.69 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.69 |
| ▸ | CDK7 | P50613 | 1/20 | 0.69 |
| ▸ | PRKX | P51817 | 1/20 | 0.69 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8525000 | 0.84 | TP53 (0.59) | CDC7CDK2FLT3GSK3BCDK5 | |
| SCHEMBL824411 | 0.84 | BCL6 (0.74) | CDC7CDK2FLT3GSK3BCDK5 | |
| SCHEMBL8524478 | 0.82 | MEN1 (0.71) | CDC7CDK2FLT3GSK3BCDK5 | |
| SCHEMBL21496120 | 0.80 | BCL6 (0.65) | CDC7CDK2FLT3GSK3BCDK5 | |
| SCHEMBL1118619 | 0.80 | MEN1 (0.68) | ABCG2EGFRKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL31002670 | 0.80 | MEN1 (0.68) | ABCG2EGFRKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL10880576 | 0.79 | BCL6 (0.62) | CDC7CDK2FLT3GSK3BCDK5 | |
| SCHEMBL24842761 | 0.78 | CTSC (0.71) | CDK2FLT3GSK3BCDK5STK17A | |
| SCHEMBL29816852 | 0.78 | CTSC (0.71) | CDK2FLT3GSK3BCDK5STK17A | |
| SCHEMBL3951217 | 0.77 | LMNA (0.53) | CDC7CDK2FLT3GSK3BCDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1629157-A | Piperazinyl triazine compounds, preparation method thereof and pharmaceutical composition containing same | SHANGHAI INST MATERIA MEDICA (CN) | 2005-06-22 | — | — | CN | disclosed |