Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 1/20 | 0.47 |
| ▸ | HTR1B | P28222 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.44 |
| ▸ | ACACB | O00763 | 4/20 | 0.44 |
| ▸ | ACACA | Q13085 | 3/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.42 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10875225 | 0.81 | HTR1D (0.47) | HTR1DHTR1BLMNAFFAR1FFAR4 | |
| SCHEMBL10874874 | 0.81 | FFAR4 (0.49) | HTR1DHTR1BLMNAFFAR1FFAR4 | |
| SCHEMBL3582664 | 0.78 | MTNR1A (0.57) | HTR1DHTR1BMTNR1AMTNR1B | |
| SCHEMBL4040995 | 0.78 | LMNA (0.57) | HTR1DHTR1BLMNAFFAR1FFAR4 | |
| SCHEMBL10875218 | 0.77 | MAOB (0.46) | HTR1DHTR1BFFAR1FFAR4 | |
| SCHEMBL10875252 | 0.76 | HTR1D (0.47) | HTR1DHTR1BLMNAFFAR1FFAR4 | |
| SCHEMBL10880776 | 0.75 | HTR1D (0.44) | HTR1DHTR1BLMNAFFAR1FFAR4 | |
| SCHEMBL10828131 | 0.75 | FFAR4 (0.56) | LMNAFFAR1FFAR4MTNR1AMTNR1B | |
| SCHEMBL10874865 | 0.74 | LMNA (0.44) | HTR1DHTR1BLMNAFFAR1FFAR4 | |
| SCHEMBL4042859 | 0.74 | USP2 (0.50) | LMNAFFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4625048-A | PESTICIDES | HOFFMANN-LA ROCHE INC. (US) | 1986-11-25 | — | — | US | disclosed |