SCHEMBL10828131

SCHEMBL10828131

O=C(O)NCCCOc1ccc(Oc2cccc(F)c2)cc1

nearest known ligand 0.56

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 5/20 0.56
FFAR1 O14842 4/20 0.56
KDM4E B2RXH2 3/20 0.52
L3MBTL1 Q9Y468 1/20 0.50
RECQL P46063 1/20 0.48
LTA4H P09960 1/20 0.47
PLA2G2A P14555 1/20 0.47
HDAC1 Q13547 1/20 0.47
HDAC2 Q92769 1/20 0.47
LMNA P02545 1/20 0.46
RAB9A P51151 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
SIRT5 Q9NXA8 1/20 0.45
LIPG Q9Y5X9 1/20 0.45
MAPT P10636 1/20 0.45
MTNR1A P48039 1/20 0.44
MTNR1B P49286 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10829128 0.86 LTA4H (0.57) KDM4EL3MBTL1RECQLLTA4HHDAC1
SCHEMBL10828184 0.86 L3MBTL1 (0.66) KDM4EL3MBTL1RECQLLTA4HPLA2G2A
SCHEMBL10828082 0.85 DRD2 (0.58) FFAR4FFAR1KDM4EL3MBTL1RECQL
SCHEMBL10828192 0.84 DRD2 (0.57) FFAR4FFAR1KDM4EL3MBTL1RECQL
SCHEMBL10828213 0.84 KDM4E (0.53) FFAR4FFAR1KDM4EL3MBTL1RECQL
SCHEMBL10828009 0.84 KDM4E (0.55) KDM4EL3MBTL1LTA4HHDAC1HDAC2
SCHEMBL10926665 0.83 MAPT (0.48) FFAR4FFAR1KDM4EL3MBTL1RAB9A
SCHEMBL9163444 0.82 PPARA (0.53) FFAR4FFAR1RAB9A
SCHEMBL9632340 0.82 LTA4H (0.55) KDM4EL3MBTL1LTA4HLMNARAB9A
SCHEMBL2353375 0.81 MTNR1A (0.65) KDM4EL3MBTL1RECQLLTA4HPLA2G2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4607051-A Carbamic acid compound and use as a pesticide HOFFMANN-LA ROCHE INC. (US) 1986-08-19 US disclosed
US-4413010-A Carbamic acid esters and use as pesticides HOFFMANN-LA ROCHE INC. (US) 1983-11-01 US disclosed