Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | FDPS | P14324 | 11/20 | 0.54 |
| ▸ | GGPS1 | O95749 | 5/20 | 0.46 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10882216 | 0.73 | FDPS (0.63) | FDPSGGPS1BTN3A1PDE3A | |
| SCHEMBL10947618 | 0.72 | PTGS2 (0.56) | FDPS | |
| SCHEMBL11307755 | 0.71 | SMN1; SMN2 (1.00) | SMN1; SMN2AKR1B1 | |
| SCHEMBL25064195 | 0.71 | AKR1B1 (0.43) | SMN1; SMN2AKR1B1 | |
| SCHEMBL10881272 | 0.71 | FDPS (0.69) | FDPSGGPS1BTN3A1PDE3A | |
| SCHEMBL3846830 | 0.69 | FDPS (1.00) | FDPSGGPS1BTN3A1PDE3A | |
| SCHEMBL11567106 | 0.68 | TAAR1 (0.46) | SMN1; SMN2AKR1B1 | |
| Phosphoric Acid SCHEMBL28200096 | 0.66 | SMN1; SMN2 (0.50) | SMN1; SMN2 | |
| SCHEMBL6980883 | 0.66 | TAAR1 (0.44) | SMN1; SMN2AKR1B1 | |
| SCHEMBL10881567 | 0.66 | FDPS (0.60) | FDPSGGPS1BTN3A1PDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0085321-B1 | DIPHOSPHONIC ACID DERIVATIVES AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM | SCHERING AKTIENGESELLSCHAFT (DE) | 1986-08-27 | — | — | EP | claimed |
| US-4473560-A | Diphosphonic acid derivatives and pharmaceutical preparations containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1984-09-25 | — | — | US | claimed |
| EP-0085321-A2 | Diphosphonic acid derivatives and pharmaceutical preparations containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1983-08-10 | — | — | EP | claimed |
| EP-0085321-B1 | DIPHOSPHONIC ACID DERIVATIVES AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM | SCHERING AKTIENGESELLSCHAFT (DE) | 1986-08-27 | — | — | EP | disclosed |
| US-4473560-A | Diphosphonic acid derivatives and pharmaceutical preparations containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1984-09-25 | — | — | US | disclosed |
| EP-0085321-A2 | Diphosphonic acid derivatives and pharmaceutical preparations containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1983-08-10 | — | — | EP | disclosed |