Phosphoric Acid

Phosphoric Acid

SCHEMBL28200096

Clc1cccc(Cl)c1Cl.NN.O=P(O)(O)O

nearest known ligand 0.50

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
JAK2 known ✓ O60674 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.50
TSHR P16473 2/20 0.48
PNMT P11086 2/20 0.44
PPP1R15A O75807 1/20 0.41
MELK Q14680 1/20 0.41
PPP1R15B Q5SWA1 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
ALDH1A1 P00352 2/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
NFKB1 P19838 1/20 0.40
TAAR1 Q96RJ0 1/20 0.40
P2RX7 Q99572 1/20 0.40
LMNA P02545 2/20 0.39
IDO1 P14902 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,2-Dichlorobenzene SCHEMBL28200714 0.84 LMNA (0.56) SMN1; SMN2TSHRPNMTALDH1A1CYP1A2
Hydrazine SCHEMBL6210937 0.84 PNMT (0.57) TSHRPNMTALDH1A1MEN1KMT2A
Hydrazine SCHEMBL28200710 0.81 PNMT (0.55) TSHRPNMTALDH1A1CYP1A2CYP3A4
Oxalic Acid SCHEMBL28200216 0.80 TSHR (0.58) SMN1; SMN2TSHRPNMTL3MBTL1ALDH1A1
Sulfuric Acid SCHEMBL28200065 0.80 TSHR (0.48) TSHRPNMTALDH1A1MEN1KMT2A
Phosphoric Acid SCHEMBL29113259 0.79 SMN1; SMN2 (0.45) SMN1; SMN2TSHRPNMTPPP1R15AMELK
Phosphoric Acid SCHEMBL20984142 0.79 MEN1 (0.50) SMN1; SMN2ALDH1A1MEN1KMT2ALMNA
1,2-Dichlorobenzene SCHEMBL27820436 0.78 LMNA (0.62) SMN1; SMN2TSHRALDH1A1CYP1A2LMNA
SCHEMBL3991309 0.78 TSHR (0.61) TSHRPNMTALDH1A1MEN1KMT2A
SCHEMBL23239 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107663161-A A kind of continuous stream synthesis technique of phenylhydrazine salt and substituted benzene hydrazonium salt 上海惠和化德生物科技有限公司 2018-02-06 CN disclosed