Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.43 |
| ▸ | PFKFB1 | P16118 | 6/20 | 0.43 |
| ▸ | PFKFB3 | Q16875 | 6/20 | 0.43 |
| ▸ | PFKFB2 | O60825 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | TERT | O14746 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20863893 | 0.85 | PFKFB1 (0.49) | CAPN1PFKFB1PFKFB3PFKFB2SMN1; SMN2 | |
| SCHEMBL22295666 | 0.85 | PFKFB1 (0.49) | CAPN1PFKFB1PFKFB3PFKFB2SMN1; SMN2 | |
| SCHEMBL7115295 | 0.85 | HDAC3 (0.44) | NAMPTMAPTHDAC3HDAC1HDAC2 | |
| SCHEMBL2409615 | 0.85 | NAMPT (0.46) | NAMPTSMN1; SMN2MAPTHPGDTERT | |
| SCHEMBL1723853 | 0.84 | CTSC (0.53) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7761782 | 0.83 | PDF (0.55) | NAMPTHDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL10790080 | 0.82 | BCL9 (0.38) | PFKFB1PFKFB3PFKFB2SMN1; SMN2MAPT | |
| SCHEMBL10790088 | 0.82 | BCL9 (0.38) | PFKFB1PFKFB3PFKFB2SMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL10789634 | 0.82 | HTR2C (0.38) | PFKFB1PFKFB3PFKFB2SMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL10790372 | 0.82 | HTR2C (0.38) | PFKFB1PFKFB3PFKFB2SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260028557-A1 | MUTANT PROTEASE | KAO CORPORATION (JP) | 2026-01-29 | — | — | US | disclosed |
| WO-2025126951-A1 | MODIFIED 5'-UNTRANSLATED REGION AND METHOD FOR PRODUCING TARGET SUBSTANCE USING SAME | 花王株式会社 | 2025-06-19 | — | — | WO | disclosed |
| EP-4563702-A1 | MUTANT PROTEASE | Kao Corporation (JP) | 2025-06-04 | — | — | EP | disclosed |
| US-12319943-B2 | Mutant protease | KAO CORPORATION (JP) | 2025-06-03 | — | — | US | disclosed |
| EP-3470517-B1 | ALKALINE PROTEASE VARIANT | KAO CORP (JP) | 2024-01-10 | — | — | EP | disclosed |
| CN-113557292-B | Mutant proteases | 花王株式会社 | 2023-10-20 | — | — | CN | disclosed |
| US-20220154109-A1 | Mutant Protease | KAO CORPORATION (JP) | 2022-05-19 | — | — | US | disclosed |
| CN-109312323-B | Mutant alkaline proteases | 花王株式会社 | 2022-03-08 | — | — | CN | disclosed |
| US-8153413-B2 | High alkaline protease and use thereof | JAPAN AGENCY FOR MARINE-EARTH SCIENCE AND TECHNOLOGY (JP) | 2012-04-10 | — | — | US | disclosed |
| EP-1660970-A4 | SYSTEMS AND METHODS FOR BIOPOLYMER ENGINEERING | DNA TWOPOINTO INC (US) | 2007-02-14 | — | — | EP | disclosed |
| EP-1660970-A2 | SYSTEMS AND METHODS FOR BIOPOLYMER ENGINEERING | DNA TWOPOINTO INC. (US) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005013090-A2 | SYSTEMS AND METHODS FOR BIOPOLYMER ENGINEERING | DNA TWOPOINTO INC. (US) | 2005-02-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260028557-A1 | MUTANT PROTEASE | IDUA, CTRL, ANPEP | NAMPT 4799/4885CAPN1 246/4885PFKFB1 4756/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.