Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | METAP1 | P53582 | 2/20 | 0.51 |
| ▸ | CES2 | O00748 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TYMS | P04818 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NQO1 | P15559 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28585350 | 0.92 | MAOA (0.55) | MAPTL3MBTL1METAP1CES2KMT2A | |
| SCHEMBL4895513 | 0.86 | NQO1 (0.52) | MAPTL3MBTL1METAP1CES2KMT2A | |
| SCHEMBL4899699 | 0.86 | NQO1 (0.52) | MAPTL3MBTL1METAP1CES2KMT2A | |
| SCHEMBL17796880 | 0.83 | MAPT (0.56) | MAPTL3MBTL1CES2KMT2ACHRNA7 | |
| SCHEMBL30426252 | 0.83 | MAPT (0.56) | MAPTL3MBTL1CES2KMT2ACHRNA7 | |
| SCHEMBL17461583 | 0.83 | MAPT (0.61) | MAPTL3MBTL1KMT2AMEN1GAA | |
| SCHEMBL10883121 | 0.82 | MAPT (0.70) | MAPTL3MBTL1KMT2ACHRNA7MEN1 | |
| SCHEMBL31066797 | 0.81 | MEN1 (0.50) | MAPTKMT2AMEN1GAANPC1 | |
| SCHEMBL25499549 | 0.81 | METAP1 (0.70) | MAPTL3MBTL1METAP1GAANPC1 | |
| SCHEMBL7764041 | 0.80 | CES2 (0.62) | MAPTL3MBTL1METAP1CES2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4792551-A | 9-anthryloxyaminoalkanes and related compounds as anti-inflammatory and analgetic agents | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0132351-A2 | 9-Anthryloxyaminoalkanes and related compounds, processes for their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1985-01-30 | — | — | EP | disclosed |