Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.47 |
| ▸ | MAP2K4 | P45985 | 10/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | MAPK6 | Q16659 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ITK | Q08881 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.37 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL874687 | 0.85 | KDM4E (0.42) | DAOKDM4EFEN1LMNAHPGD | |
| SCHEMBL10987571 | 0.78 | JAK2 (0.50) | — | |
| SCHEMBL10883616 | 0.78 | DAO (0.47) | DAOMAP2K4MAPK1KDM4ELMNA | |
| SCHEMBL874382 | 0.74 | KIF11 (0.48) | KDM4E | |
| SCHEMBL12320106 | 0.72 | ALPL (0.42) | DAOMAP2K4KDM4E | |
| SCHEMBL547904 | 0.72 | CYP1A2 (0.46) | MAP2K4KDM4ELMNAHPGDALDH1A1 | |
| SCHEMBL929511 | 0.70 | DAO (0.47) | DAOMAP2K4MAPK1MAPK6KDM4E | |
| SCHEMBL29798728 | 0.70 | PARP1 (0.50) | DAOKDM4EFEN1HTR2A | |
| SCHEMBL30089426 | 0.70 | DAO (0.43) | DAOMAP2K4KDM4ELMNAALDH1A1 | |
| SCHEMBL10639617 | 0.70 | PDE3B (0.44) | KDM4ELMNAHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0108352-B1 | 3-(3-IODOPROPARGYL)-BENZO-1,2,3-TRIAZIN-4-ONES, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION AS MICROBICIDES | BAYER AG (DE) | 1986-04-02 | — | — | EP | disclosed |
| US-4520023-A | FUNGICIDES, BACTERICIDES, ALGICIDES, SLIMICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1985-05-28 | — | — | US | disclosed |
| EP-0108352-A2 | 3-(3-Iodopropargyl)-benzo-1,2,3-triazin-4-ones, process for their preparation and their application as microbicides | BAYER AG (DE) | 1984-05-16 | — | — | EP | disclosed |