SCHEMBL10883292

SCHEMBL10883292

CCCCCCC(CC)CC(C)(CCCC)P(=O)(O)O

nearest known ligand 0.46

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FDPS P14324 14/20 0.46
GGPS1 O95749 6/20 0.43
SMPD1 P17405 3/20 0.41
LPAR1 Q92633 1/20 0.41
LPAR3 Q9UBY5 1/20 0.41
LAP3 P28838 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2776464 0.94 GGPS1 (0.47) FDPSGGPS1SMPD1LPAR1LPAR3
SCHEMBL31037548 0.92 GGPS1 (0.46) FDPSGGPS1SMPD1LPAR1LPAR3
SCHEMBL3980053 0.77 GGPS1 (0.63) FDPSGGPS1SMPD1LPAR1LPAR3
SCHEMBL27574135 0.77 GGPS1 (0.63) FDPSGGPS1SMPD1LPAR1LPAR3
SCHEMBL29948582 0.77 CYP3A4 (0.39) FDPSGGPS1SMPD1LPAR1LPAR3
SCHEMBL4428516 0.76 GGPS1 (0.49) FDPSGGPS1SMPD1LPAR1LPAR3
SCHEMBL24067447 0.75 GGPS1 (0.65) FDPSGGPS1SMPD1LPAR1LPAR3
SCHEMBL19840566 0.75 GGPS1 (0.65) FDPSGGPS1SMPD1LPAR1LPAR3
SCHEMBL19961999 0.75 GGPS1 (0.65) FDPSGGPS1SMPD1LPAR1LPAR3
SCHEMBL3890040 0.75 FDPS (0.58) FDPSGGPS1SMPD1LPAR1LPAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0053964-B1 1(4-QUINOLYL)ETHANOL OR PROPANOL DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESSES FOR THEIR PREPARATION PHARMUKA LABORATOIRES (FR) 1986-05-07 EP claimed