Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGPS1 | O95749 | 7/20 | 0.47 |
| ▸ | FDPS | P14324 | 15/20 | 0.46 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.45 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.45 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31037548 | 0.98 | GGPS1 (0.46) | GGPS1FDPSSMPD1LPAR1LPAR3 | |
| SCHEMBL10883292 | 0.94 | FDPS (0.46) | GGPS1FDPSSMPD1LPAR1LPAR3 | |
| SCHEMBL29948582 | 0.83 | CYP3A4 (0.39) | GGPS1FDPSSMPD1LPAR1LPAR3 | |
| SCHEMBL4428516 | 0.83 | GGPS1 (0.49) | GGPS1FDPSSMPD1LPAR1LPAR3 | |
| SCHEMBL4323349 | 0.79 | FDPS (0.44) | GGPS1FDPSSMPD1LPAR1LPAR3 | |
| SCHEMBL24067447 | 0.79 | GGPS1 (0.65) | GGPS1FDPSSMPD1LPAR1LPAR3 | |
| SCHEMBL19961999 | 0.79 | GGPS1 (0.65) | GGPS1FDPSSMPD1LPAR1LPAR3 | |
| SCHEMBL19840566 | 0.79 | GGPS1 (0.65) | GGPS1FDPSSMPD1LPAR1LPAR3 | |
| SCHEMBL5548513 | 0.78 | CYP3A4 (0.46) | GGPS1FDPSCYP3A4L3MBTL1 | |
| SCHEMBL27574135 | 0.77 | GGPS1 (0.63) | GGPS1FDPSSMPD1LPAR1LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100004413-A1 | BULK POLYMERIZATION PROCESS FOR PRODUCING POLYDIENES | BRIDGESTONE CORPORATION (JP) | 2010-01-07 | — | — | US | claimed |
| EP-3077455-B1 | PROCESS FOR PREPARING BLENDS OF CIS-1,4-POLYBUTADIENE AND SYNDIOTACTIC 1,2-POLYBUTADIENE | BRIDGESTONE CORP (JP) | 2020-08-12 | — | — | EP | disclosed |
| US-10066035-B2 | Catalyst systems and methods for preparation of 1,4-polybutadiene rubber | BRIDGESTONE CORPORATION (JP) | 2018-09-04 | — | — | US | disclosed |
| US-10035908-B1 | Process for preparing blends of trans-1,4-polybutadiene and syndiotactic 1,2-polybutadiene | BRIDGESTONE CORPORATION (JP) | 2018-07-31 | — | — | US | disclosed |
| US-9803032-B2 | Processes for the preparation of high-cis polydienes | BRIDGESTON CORPORATION (JP) | 2017-10-31 | — | — | US | disclosed |
| US-20170158787-A1 | Catalyst Systems And Methods For Preparation Of 1,4-Polybutadiene Rubber | BRIDGESTONE CORPORATION (JP) | 2017-06-08 | — | — | US | disclosed |
| US-9469741-B2 | Polymers functionalized with heterocyclic nitrile compounds | BRIDGESTONE CORPORATION (JP) | 2016-10-18 | — | — | US | disclosed |
| US-9249244-B2 | Process for producing polydienes | BRIDGESTONE CORPORATION (JP) | 2016-02-02 | — | — | US | disclosed |
| EP-2707403-B1 | PROCESSES FOR THE PREPARATION OF HIGH-CIS POLYDIENES | BRIDGESTONE CORP (JP) | 2015-07-29 | — | — | EP | disclosed |
| US-9000107-B2 | Process for producing polydienes | BRIDGESTONE CORPORATION (JP) | 2015-04-07 | — | — | US | disclosed |
| US-7906592-B2 | Polymers functionalized with imide compounds containing a protected amino group | BRIDGESTONE CORPORATION (JP) | 2011-03-15 | — | — | US | disclosed |
| US-20100168378-A1 | POLYMERS FUNCTIONALIZED WITH NITROSO COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2010-07-01 | — | — | US | disclosed |
| US-20100004413-A1 | BULK POLYMERIZATION PROCESS FOR PRODUCING POLYDIENES | BRIDGESTONE CORPORATION (JP) | 2010-01-07 | — | — | US | disclosed |
| US-20100004414-A1 | POLYMERS FUNCTIONALIZED WITH IMIDE COMPOUNDS CONTAINING A PROTECTED AMINO GROUP | BRIDGESTONE CORPORATION (JP) | 2010-01-07 | — | — | US | disclosed |
| US-20080255327-A1 | addition polymerization of conjugated polyene monomer in the presence of polymerization catalysts comprising a mixture of a nickel-containing compound, an alkylating agent, a fluorine-containing compound, a carboxylic acid and an alcohol; controlling gelation, branching and molecular weight; efficiency | BRIDGESTONE CORPORATION (JP) | 2008-10-16 | — | — | US | disclosed |
| US-7008899-B2 | Lanthanide-based catalyst composition for producing cis-1,4-polydienes | BRIDGESTONE CORPORATION (JP) | 2006-03-07 | — | — | US | disclosed |
| US-20050038215-A1 | Lanthanide-based catalyst composition for producing cis-1,4-polydienes | BRIDGESTONE CORPORATION (JP) | 2005-02-17 | — | — | US | disclosed |
| US-20040116638-A1 | Continuous process for the production of conjugated diene polymers having narrow molecular weight distribution and products therefrom | BRIDGESTONE CORPORATION (JP) | 2004-06-17 | — | — | US | disclosed |
| US-6320004-B1 | FORMED BY COMBINING (A) A IRON-CONTAINING COMPOUND; (B) AN ORGANOMAGNESIUM COMPOUND; AND (C) A SILYL PHOSPHONATE; POLYMERIZING CONJUGATED DIENE MONOMERS | BRIDGESTONE CORPORATION (JP) | 2001-11-20 | — | — | US | disclosed |
| US-6303692-B1 | PROVIDING MIXTURE OF RUBBER CEMENT AND 1,3-BUTADIENE; POLYMERIZING INTO SYNDIOTACTIC 1,2-POLYBUTADIENE BY USING CATALYST FORMULATION COMPRISING MOLYBDENUM COMPOUND, HYDROGEN PHOSPHITE COMPOUND AND ORGANOALUMINUM COMPOUND | BRIDGESTONE CORPORATION (JP) | 2001-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100004414-A1 | POLYMERS FUNCTIONALIZED WITH IMIDE COMPOUNDS CONTAINING A PROTECTED AMINO GROUP | PARG, PIN1, NPEPPS | GGPS1 1794/4885FDPS 2251/4885SMPD1 4859/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.