Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGPS1 | O95749 | 7/20 | 0.49 |
| ▸ | FDPS | P14324 | 15/20 | 0.47 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.46 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4323349 | 0.94 | FDPS (0.44) | GGPS1FDPSSMPD1LPAR1LPAR3 | |
| SCHEMBL2776464 | 0.83 | GGPS1 (0.47) | GGPS1FDPSSMPD1LPAR1LPAR3 | |
| SCHEMBL31037548 | 0.81 | GGPS1 (0.46) | GGPS1FDPSSMPD1LPAR1LPAR3 | |
| SCHEMBL11438984 | 0.80 | GGPS1 (0.55) | GGPS1FDPSSMPD1LPAR1LPAR3 | |
| SCHEMBL2440934 | 0.79 | CA2 (0.46) | CYP3A4 | |
| SCHEMBL11185505 | 0.79 | CA2 (0.46) | CYP3A4 | |
| SCHEMBL6896582 | 0.78 | GGPS1 (0.68) | GGPS1FDPSSMPD1LPAR1LPAR3 | |
| SCHEMBL21101802 | 0.78 | GGPS1 (0.68) | GGPS1FDPSSMPD1LPAR1LPAR3 | |
| SCHEMBL6896475 | 0.78 | GGPS1 (0.68) | GGPS1FDPSSMPD1LPAR1LPAR3 | |
| SCHEMBL11406652 | 0.78 | GGPS1 (0.68) | GGPS1FDPSSMPD1LPAR1LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1509085-B1 | PHOSPHONATES AND DERIVATIVES THEREOF AS ENHANCERS OF THE ACTIVITY OF INSECTICIDES | SYNGENTA LTD (GB) | 2009-07-15 | — | — | EP | claimed |
| US-20060093637-A1 | Phosphonates and derivatives thereof as enhancers of the activity of insecticides | ADAMA CELSIUS B.V. CURACAO | 2006-05-04 | — | — | US | claimed |
| EP-1509085-A1 | PHOSPHONATES AND DERIVATIVES THEREOF AS ENHANCERS OF THE ACTIVITY OF INSECTICIDES | Syngenta Limited (GB) | 2005-03-02 | — | — | EP | claimed |
| WO-2003099012-A1 | PHOSPHONATES AND DERIVATIVES THEREOF AS ENHANCERS OF THE ACTIVITY OF INSECTICIDES | SYNGENTA LIMITED (GB) | 2003-12-04 | — | — | WO | claimed |
| US-9138003-B2 | Phosphonates and derivatives thereof as enhancers of the activity of insecticides | SYNGENTA CROP PROTECTION INC. (US) | 2015-09-22 | — | — | US | disclosed |
| US-9138003-B2 | Phosphonates and derivatives thereof as enhancers of the activity of insecticides | SYNGENTA CROP PROTECTION INC. (US) | 2015-09-22 | — | — | US | disclosed |
| EP-1509085-B1 | PHOSPHONATES AND DERIVATIVES THEREOF AS ENHANCERS OF THE ACTIVITY OF INSECTICIDES | SYNGENTA LTD (GB) | 2009-07-15 | — | — | EP | disclosed |
| EP-1509085-B1 | PHOSPHONATES AND DERIVATIVES THEREOF AS ENHANCERS OF THE ACTIVITY OF INSECTICIDES | SYNGENTA LTD (GB) | 2009-07-15 | — | — | EP | disclosed |
| EP-1515609-B1 | HERBICIDAL COMPOSITION | SYNGENTA LTD (GB) | 2008-04-23 | — | — | EP | disclosed |
| CN-100333643-C | Phosphonates and derivatives thereof as enhancers of the activity of insecticides | SYNGENTA CO LTD (GB) | 2007-08-29 | — | — | CN | disclosed |
| US-20060093637-A1 | Phosphonates and derivatives thereof as enhancers of the activity of insecticides | ADAMA CELSIUS B.V. CURACAO | 2006-05-04 | — | — | US | disclosed |
| US-20060093637-A1 | Phosphonates and derivatives thereof as enhancers of the activity of insecticides | ADAMA CELSIUS B.V. CURACAO | 2006-05-04 | — | — | US | disclosed |
| CN-1655679-A | Phosphonates and derivatives thereof as enhancers of the activity of insecticides | SYNGENTA LTD (GB) | 2005-08-17 | — | — | CN | disclosed |
| EP-1509085-A1 | PHOSPHONATES AND DERIVATIVES THEREOF AS ENHANCERS OF THE ACTIVITY OF INSECTICIDES | Syngenta Limited (GB) | 2005-03-02 | — | — | EP | disclosed |
| EP-1509085-A1 | PHOSPHONATES AND DERIVATIVES THEREOF AS ENHANCERS OF THE ACTIVITY OF INSECTICIDES | Syngenta Limited (GB) | 2005-03-02 | — | — | EP | disclosed |
| WO-2003099012-A1 | PHOSPHONATES AND DERIVATIVES THEREOF AS ENHANCERS OF THE ACTIVITY OF INSECTICIDES | SYNGENTA LIMITED (GB) | 2003-12-04 | — | — | WO | disclosed |
| WO-2003099012-A1 | PHOSPHONATES AND DERIVATIVES THEREOF AS ENHANCERS OF THE ACTIVITY OF INSECTICIDES | SYNGENTA LIMITED (GB) | 2003-12-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060093637-A1 | Phosphonates and derivatives thereof as enhancers of the activity of insecticides | PHOSPHO1, PTEN, PPIP5K2 | GGPS1 323/4885FDPS 972/4885SMPD1 909/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.