Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 5/20 | 0.55 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10886194 | 0.92 | ADORA2A (0.54) | ADORA2AADORA2BADORA3 | |
| SCHEMBL11202218 | 0.92 | ADORA2A (0.54) | ADORA2AADORA2BADORA3 | |
| SCHEMBL10888025 | 0.90 | ADORA2A (0.57) | ADORA2AADORA2BADORA3 | |
| SCHEMBL11215188 | 0.90 | ADORA2A (0.57) | ADORA2AADORA2BADORA3 | |
| SCHEMBL10884518 | 0.86 | DOT1L (0.50) | ADORA2AADORA2B | |
| SCHEMBL10886624 | 0.85 | AHCY (0.65) | ADORA2AADORA2BADORA3 | |
| SCHEMBL10885358 | 0.84 | ADORA2A (0.51) | ADORA2AADORA2BADORA3 | |
| SCHEMBL10884710 | 0.82 | ADORA3 (0.60) | ADORA2AADORA2BADORA3 | |
| SCHEMBL11195576 | 0.82 | ADORA3 (0.60) | ADORA2AADORA2BADORA3 | |
| SCHEMBL10885217 | 0.82 | ADORA2A (0.53) | ADORA2AADORA2BADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0071926-B1 | NEW RIBOFURANURONIC ACID DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-10-08 | — | — | EP | disclosed |
| US-4479942-A | Tetrahydrofurnancarboxylic acid derivatives, processes for preparation thereof and pharmaceutical compositions thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-10-30 | — | — | US | disclosed |
| EP-0071926-A1 | New ribofuranuronic acid derivatives, processes for preparation thereof and pharmaceutical compositions thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-02-16 | — | — | EP | disclosed |