Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.60 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.60 |
| ▸ | ADORA2A | P29274 | 8/20 | 0.58 |
| ▸ | ADORA2B | P29275 | 8/20 | 0.58 |
| ▸ | AHCY | P23526 | 2/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11195576 | 1.00 | ADORA3 (0.60) | ADORA3ADORA1ADORA2AADORA2BAHCY | |
| SCHEMBL10889457 | 0.91 | ADORA3 (0.58) | ADORA3ADORA1ADORA2AADORA2BAHCY | |
| SCHEMBL11215188 | 0.88 | ADORA2A (0.57) | ADORA3ADORA2AADORA2B | |
| SCHEMBL10888025 | 0.88 | ADORA2A (0.57) | ADORA3ADORA2AADORA2B | |
| SCHEMBL19146527 | 0.87 | ADORA3 (0.62) | ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL13964749 | 0.86 | ADORA2A (0.58) | ADORA3ADORA2AADORA2BAHCYHIF1A | |
| SCHEMBL19190143 | 0.86 | ADORA2A (0.58) | ADORA3ADORA2AADORA2BAHCYHIF1A | |
| SCHEMBL13974841 | 0.86 | ADORA2A (0.58) | ADORA3ADORA2AADORA2BAHCYHIF1A | |
| SCHEMBL13964740 | 0.86 | ADORA2A (0.58) | ADORA3ADORA2AADORA2BAHCYHIF1A | |
| SCHEMBL23169438 | 0.83 | LMNA (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0071926-B1 | NEW RIBOFURANURONIC ACID DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-10-08 | — | — | EP | disclosed |
| US-4479942-A | Tetrahydrofurnancarboxylic acid derivatives, processes for preparation thereof and pharmaceutical compositions thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-10-30 | — | — | US | disclosed |
| EP-0071926-A1 | New ribofuranuronic acid derivatives, processes for preparation thereof and pharmaceutical compositions thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-02-16 | — | — | EP | disclosed |