Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 1/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 6/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.45 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10885229 | 0.89 | ADORA2A (0.52) | AHCYADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL10887386 | 0.88 | ADORA2A (0.52) | AHCYADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL10885276 | 0.88 | ADORA2A (0.52) | AHCYADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL11054733 | 0.88 | AHCY (0.68) | AHCYADORA2AADORA3DOT1L | |
| SCHEMBL10883897 | 0.85 | ADORA2A (0.48) | AHCYADORA2AADORA2BDOT1L | |
| SCHEMBL10886574 | 0.84 | ADORA2A (0.49) | AHCYADORA2AADORA2B | |
| SCHEMBL10885822 | 0.80 | ADORA2A (0.46) | AHCYADORA2AADORA2B | |
| SCHEMBL10885962 | 0.78 | ADORA2A (0.46) | AHCYADORA2AADORA2BDOT1L | |
| SCHEMBL10884518 | 0.78 | DOT1L (0.50) | AHCYADORA2AADORA2BDOT1L | |
| SCHEMBL11195576 | 0.77 | ADORA3 (0.60) | AHCYADORA2AADORA2BADORA3ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0071926-B1 | NEW RIBOFURANURONIC ACID DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-10-08 | — | — | EP | disclosed |
| US-4479942-A | Tetrahydrofurnancarboxylic acid derivatives, processes for preparation thereof and pharmaceutical compositions thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-10-30 | — | — | US | disclosed |
| EP-0071926-A1 | New ribofuranuronic acid derivatives, processes for preparation thereof and pharmaceutical compositions thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-02-16 | — | — | EP | disclosed |