Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | ESR1 | P03372 | 5/20 | 0.50 |
| ▸ | EBP | Q15125 | 3/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.48 |
| ▸ | DRD3 | P35462 | 2/20 | 0.48 |
| ▸ | HTR6 | P50406 | 2/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | IDH1 | O75874 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10886087 | 0.94 | EBP (0.57) | KDM4EESR1EBPSIGMAR1HRH3 | |
| SCHEMBL10886615 | 0.87 | EBP (0.56) | KDM4EESR1EBPSIGMAR1HRH3 | |
| SCHEMBL10883839 | 0.82 | ESR1 (0.47) | KDM4EESR1EBPSIGMAR1HRH3 | |
| SCHEMBL10888476 | 0.80 | EBP (0.66) | KDM4EESR1EBPSIGMAR1HRH3 | |
| SCHEMBL10884852 | 0.79 | EBP (0.56) | KDM4EESR1EBPSIGMAR1HRH3 | |
| SCHEMBL10885006 | 0.79 | EBP (0.55) | KDM4EESR1EBPSIGMAR1HRH3 | |
| SCHEMBL10887794 | 0.76 | EBP (0.53) | KDM4EESR1EBPSIGMAR1HRH3 | |
| SCHEMBL3445367 | 0.75 | KDM4E (0.68) | KDM4EEBPSIGMAR1HRH3KCNH2 | |
| SCHEMBL10887413 | 0.74 | BCHE (0.64) | KDM4EEBPSIGMAR1HRH3BCHE | |
| SCHEMBL10879326 | 0.74 | SIGMAR1 (0.51) | KDM4EESR1EBPSIGMAR1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0115080-B1 | (OMEGA-(DIETHYLAMINO)-ALKOXY)-ALPHA-(ETHYL)-BENZHYDROL DERIVATIVES, THEIR ACID ADDITION SALTS AND QUATERNARY SALTS, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THESE COMPOUNDS | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1986-04-16 | — | — | EP | claimed |
| EP-0115080-B1 | (OMEGA-(DIETHYLAMINO)-ALKOXY)-ALPHA-(ETHYL)-BENZHYDROL DERIVATIVES, THEIR ACID ADDITION SALTS AND QUATERNARY SALTS, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THESE COMPOUNDS | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1986-04-16 | — | — | EP | disclosed |