Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EBP | Q15125 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.51 |
| ▸ | BCHE | P06276 | 2/20 | 0.49 |
| ▸ | ACHE | P22303 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | FOXM1 | Q08050 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10886615 | 0.86 | EBP (0.56) | EBPSIGMAR1HRH3BCHEACHE | |
| SCHEMBL10887720 | 0.79 | ALDH1A1 (0.51) | EBPSIGMAR1HRH3BCHEACHE | |
| SCHEMBL10885086 | 0.79 | KDM4E (0.51) | EBPSIGMAR1HRH3BCHEACHE | |
| SCHEMBL10883839 | 0.79 | ESR1 (0.47) | EBPSIGMAR1HRH3BCHEACHE | |
| SCHEMBL10888476 | 0.78 | EBP (0.66) | EBPSIGMAR1HRH3BCHEACHE | |
| SCHEMBL10880850 | 0.78 | HRH3 (0.48) | EBPSIGMAR1HRH3KDM4ESMN1; SMN2 | |
| SCHEMBL10890295 | 0.78 | EBP (0.61) | EBPSIGMAR1HRH3BCHEACHE | |
| SCHEMBL492102 | 0.78 | HRH3 (0.61) | EBPSIGMAR1HRH3BCHEACHE | |
| SCHEMBL10794613 | 0.76 | BCHE (0.56) | BCHEACHEKDM4ESMN1; SMN2 | |
| SCHEMBL491797 | 0.76 | L3MBTL1 (0.69) | EBPSIGMAR1HRH3BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0115080-B1 | (OMEGA-(DIETHYLAMINO)-ALKOXY)-ALPHA-(ETHYL)-BENZHYDROL DERIVATIVES, THEIR ACID ADDITION SALTS AND QUATERNARY SALTS, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THESE COMPOUNDS | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1986-04-16 | — | — | EP | claimed |
| EP-0115080-B1 | (OMEGA-(DIETHYLAMINO)-ALKOXY)-ALPHA-(ETHYL)-BENZHYDROL DERIVATIVES, THEIR ACID ADDITION SALTS AND QUATERNARY SALTS, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THESE COMPOUNDS | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1986-04-16 | — | — | EP | disclosed |