Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 8/20 | 0.64 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10664719 | 0.99 | FAAH (0.62) | FAAHCACNA1GATMSIGMAR1NPC1 | |
| SCHEMBL10890218 | 0.93 | CACNA1G (0.63) | FAAHCACNA1GATMSIGMAR1NPC1 | |
| Hydrochloric Acid SCHEMBL10662984 | 0.92 | CACNA1G (0.61) | FAAHCACNA1GATMSIGMAR1NPC1 | |
| SCHEMBL10912688 | 0.85 | FAAH (0.54) | FAAHCACNA1GATMSIGMAR1 | |
| Hydrochloric Acid SCHEMBL10663950 | 0.84 | CACNA1G (0.65) | FAAHCACNA1GATMNPC1TP53 | |
| Hydrochloric Acid SCHEMBL10660475 | 0.83 | CACNA1G (0.56) | FAAHCACNA1GATMNPC1TP53 | |
| Hydrochloric Acid SCHEMBL10663046 | 0.83 | FAAH (0.52) | FAAHCACNA1G | |
| SCHEMBL10886369 | 0.81 | CACNA1G (0.61) | FAAHCACNA1GATMNPC1TP53 | |
| Hydrochloric Acid SCHEMBL10662378 | 0.81 | FAAH (0.61) | FAAHCACNA1GNPC1TP53POLB | |
| Hydrochloric Acid SCHEMBL10662908 | 0.81 | CACNA1G (0.60) | FAAHCACNA1GATMNPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0127182-B1 | 1-PHENYLALKYL-4-(MERCAPTO AND CARBAMYLTHIO)ALKYL-PIPERAZINES AND -HOMOPIPERAZINES AND THEIR USE IN THE TREATMENT OF ALLERGIC DISEASES | Boehringer Ingelheim Pharmaceuticals Inc. (US) | 1986-12-30 | — | — | EP | claimed |