Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.54 |
| ▸ | CACNA1G | O43497 | 4/20 | 0.53 |
| ▸ | HTR1A | P08908 | 2/20 | 0.52 |
| ▸ | DRD2 | P14416 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10663046 | 0.98 | FAAH (0.52) | FAAHCACNA1GHTR1ADRD2ALDH1A1 | |
| SCHEMBL10890218 | 0.92 | CACNA1G (0.63) | FAAHCACNA1GALDH1A1NPSR1ATM | |
| Hydrochloric Acid SCHEMBL10662984 | 0.91 | CACNA1G (0.61) | FAAHCACNA1GALDH1A1NPSR1ATM | |
| Hydrochloric Acid SCHEMBL10661798 | 0.90 | FAAH (0.60) | FAAHHTR1ADRD2ALDH1A1NPSR1 | |
| SCHEMBL10910575 | 0.88 | CACNA1G (0.50) | FAAHCACNA1GALDH1A1NPSR1HRH3 | |
| Hydrochloric Acid SCHEMBL10657646 | 0.87 | CACNA1G (0.49) | CACNA1GALDH1A1NPSR1HRH3SIGMAR1 | |
| SCHEMBL10911211 | 0.86 | KCNA5 (0.53) | FAAHCACNA1GDRD2ALDH1A1HRH3 | |
| Hydrochloric Acid SCHEMBL10664935 | 0.85 | KCNA5 (0.52) | FAAHCACNA1GDRD2ALDH1A1HRH3 | |
| SCHEMBL10885100 | 0.85 | FAAH (0.64) | FAAHCACNA1GATMSIGMAR1 | |
| Hydrochloric Acid SCHEMBL10663862 | 0.85 | FAAH (0.64) | FAAHALDH1A1NPSR1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4618677-A | Substituted phenylalkyl-(piperazinyl or homopiperazinyl)alkyl-thiols and -thiocarbamates useful for the treatment of immunological, inflammatory, and allergic disorders | BOEHRINGER INGELHEIM LIMITED (US) | 1986-10-21 | — | — | US | claimed |