Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5899076 | 0.80 | EGLN3 (0.55) | EGLN3MAPTHTTCYP1A2CYP3A4 | |
| SCHEMBL8926508 | 0.76 | EGLN3 (0.42) | EGLN3MAPTHTTSMN1; SMN2FDPS | |
| SCHEMBL4291631 | 0.73 | EGLN3 (0.48) | EGLN3MAPTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL22234971 | 0.73 | EGLN3 (0.48) | EGLN3MAPTHTTCYP1A2CYP3A4 | |
| SCHEMBL7765796 | 0.72 | — | — | |
| SCHEMBL7104938 | 0.70 | EGLN3 (0.50) | EGLN3MAPTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL10465846 | 0.70 | MAPT (0.53) | MAPTHTTLMNAPKM | |
| SCHEMBL8926510 | 0.69 | EGLN3 (0.44) | EGLN3MAPTHTTSMN1; SMN2LMNA | |
| SCHEMBL10882663 | 0.69 | FDPS (0.53) | EGLN3MAPTHTTFDPS | |
| SCHEMBL10900681 | 0.69 | EGLN3 (0.49) | EGLN3MAPTCYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0078613-B1 | SUBSTITUTED PROPYL PHOSPHONIC ACID DERIVATIVES, THEIR USE AS HERBICIDES, HERBICIDAL COMPOSITIONS CONTAINING THEM, AND METHODS OF PREPARING THEM | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-10-01 | — | — | EP | disclosed |
| US-4439428-A | 1,2,4-TRIAZOL-1-YL-ALKYLENE PHOSPHONIC ACIDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-03-27 | — | — | US | disclosed |