Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.41 |
| ▸ | PARP1 | P09874 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10883616 | 0.85 | DAO (0.47) | LMNAHPGDGRIN2DGRIN3BGRIN1 | |
| SCHEMBL874076 | 0.78 | ALDH1A1 (0.44) | LMNAHPGDCHEK1PARP1MEN1 | |
| SCHEMBL874687 | 0.78 | KDM4E (0.42) | LMNAGAAHPGDPARP1KDM4E | |
| SCHEMBL10879458 | 0.73 | MAPT (0.52) | LMNAHPGDPARP1CA12CA9 | |
| SCHEMBL203784 | 0.72 | F7 (0.48) | GAAHPGDGRIN2DGRIN3BGRIN1 | |
| SCHEMBL547904 | 0.72 | CYP1A2 (0.46) | LMNACYP1A2GAAHPGDGRIN2D | |
| SCHEMBL30918933 | 0.72 | LMNA (0.53) | LMNACYP1A2GAAHPGDGRIN2D | |
| SCHEMBL11474182 | 0.71 | LMNA (0.45) | LMNACYP1A2GAAHPGDGRIN2D | |
| Hydrochloric Acid SCHEMBL29618028 | 0.71 | F7 (0.47) | HPGDGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL1150908 | 0.71 | F7 (0.47) | HPGDGRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0196617-A1 | [4.2.0]bicyclooctane derivatives, process for their preparation and pharmaceutical compositions containing same | SYNTEX (U.S.A.) INC. (US) | 1986-10-08 | — | — | EP | disclosed |
| EP-0108352-B1 | 3-(3-IODOPROPARGYL)-BENZO-1,2,3-TRIAZIN-4-ONES, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION AS MICROBICIDES | BAYER AG (DE) | 1986-04-02 | — | — | EP | disclosed |
| US-4520023-A | FUNGICIDES, BACTERICIDES, ALGICIDES, SLIMICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1985-05-28 | — | — | US | disclosed |
| EP-0108352-A2 | 3-(3-Iodopropargyl)-benzo-1,2,3-triazin-4-ones, process for their preparation and their application as microbicides | BAYER AG (DE) | 1984-05-16 | — | — | EP | disclosed |