Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | MAP2K4 | P45985 | 6/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.42 |
| ▸ | MAPKAPK3 | Q16644 | 3/20 | 0.42 |
| ▸ | MAPK6 | Q16659 | 3/20 | 0.42 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.42 |
| ▸ | MAPKAPK5 | Q8IW41 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10885158 | 0.78 | LMNA (0.43) | ALDH1A1CHEK1MEN1KMT2AKDM4E | |
| SCHEMBL874687 | 0.78 | KDM4E (0.42) | ALDH1A1KDM4EHPGDLMNASMN1; SMN2 | |
| SCHEMBL9511534 | 0.73 | ITK (0.42) | ALDH1A1CHEK1MAP2K4MAPK1MAPKAPK3 | |
| SCHEMBL10879458 | 0.73 | MAPT (0.52) | ALDH1A1MEN1NPC1KMT2APOLB | |
| SCHEMBL103309 | 0.72 | CYP1A2 (0.39) | ALDH1A1CHEK1MAP2K4MAPK1MAPKAPK3 | |
| SCHEMBL547904 | 0.72 | CYP1A2 (0.46) | ALDH1A1MAP2K4MEN1NPC1KMT2A | |
| SCHEMBL29367601 | 0.72 | CYP1A2 (0.39) | ALDH1A1CHEK1MAP2K4MAPK1MAPKAPK3 | |
| SCHEMBL11455288 | 0.71 | NPC1 (0.51) | ALDH1A1CHEK1MAPK1MEN1NPC1 | |
| SCHEMBL1537875 | 0.71 | CYP1A2 (0.38) | ALDH1A1CHEK1MAP2K4MAPK1MAPKAPK3 | |
| Ammonia Solution, Strong SCHEMBL1814826 | 0.71 | CYP1A2 (0.38) | ALDH1A1CHEK1MAP2K4MAPK1MAPKAPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140148459-A1 | MATRIX METALLOPROTEINASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2014-05-29 | — | — | US | disclosed |
| EP-2619185-A1 | MATRIX METALLOPROTEINASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2013-07-31 | — | — | EP | disclosed |
| EP-2619179-A1 | MATRIX METALLOPROTEINASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2013-07-31 | — | — | EP | disclosed |
| WO-2012038944-A1 | MATRIX METALLOPROTEINASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-03-29 | — | — | WO | disclosed |
| WO-2012038942-A1 | MATRIX METALLOPROTEINASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-03-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140148459-A1 | MATRIX METALLOPROTEINASE INHIBITORS | MMP9, MMP12, MMP10 | ALDH1A1 2281/4885CHEK1 3829/4885MAP2K4 831/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.