Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 1/20 | 0.57 |
| ▸ | NLRP3 | Q96P20 | 8/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10779722 | 0.86 | MAPK1 (0.57) | F2RNLRP3LMNAMAPK1ALDH1A1 | |
| SCHEMBL29648979 | 0.85 | NLRP3 (0.52) | F2RNLRP3HSD17B10KDM4ELMNA | |
| SCHEMBL22987464 | 0.85 | NLRP3 (0.52) | F2RNLRP3HSD17B10KDM4ELMNA | |
| SCHEMBL10884104 | 0.83 | RAB9A (0.56) | KDM4ELMNAMAPTMAPK1ALDH1A1 | |
| SCHEMBL9359788 | 0.81 | NLRP3 (0.78) | NLRP3HSD17B10KDM4ELMNAMAPT | |
| SCHEMBL10781336 | 0.81 | SMN1; SMN2 (0.44) | NLRP3HSD17B10LMNAMAPTMAPK1 | |
| SCHEMBL1188292 | 0.81 | ALDH1A1 (0.62) | F2RNLRP3HSD17B10KDM4ELMNA | |
| SCHEMBL29209712 | 0.79 | ALDH1A1 (0.68) | F2RNLRP3HSD17B10KDM4ELMNA | |
| SCHEMBL2090679 | 0.79 | NLRP3 (0.79) | NLRP3HSD17B10KDM4ELMNAMAPT | |
| SCHEMBL10776408 | 0.78 | NLRP3 (0.39) | F2RNLRP3LMNAMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0123412-B1 | METHOD FOR MANUFACTURE OF DIPHENYLMETHANE DIISOCYANATES | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1986-07-09 | — | — | EP | disclosed |
| US-4552974-A | Process for producing diphenylmethane dicarbamates | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1985-11-12 | — | — | US | disclosed |
| US-4547322-A | Method for manufacture of diphenylmethane diisocyanates | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1985-10-15 | — | — | US | disclosed |
| EP-0123412-A1 | Method for manufacture of diphenylmethane diisocyanates | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1984-10-31 | — | — | EP | disclosed |
| EP-0110732-A2 | Process for producing diphenylmethane dicarbamates | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1984-06-13 | — | — | EP | disclosed |