SCHEMBL10885202

SCHEMBL10885202

N#COc1ccccc1C(Cl)(Cl)Cl

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.36
AR P10275 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27228587 0.79 SGMS2 (0.36) TSHRAR
SCHEMBL8983336 0.79 TSHR (0.31) TSHR
SCHEMBL30003749 0.79 TDP1 (0.41) TSHR
SCHEMBL5586106 0.79 SGMS2 (0.36) TSHRAR
SCHEMBL3826953 0.79 TDP1 (0.41) TSHR
SCHEMBL17914533 0.79 AR (0.40) AR
SCHEMBL159732 0.77 CA1 (0.38) TSHR
SCHEMBL30159634 0.77 CA1 (0.38) TSHR
SCHEMBL11851873 0.76 LMNA (0.42) TSHRAR
SCHEMBL5176422 0.75 TSHR (0.38) TSHRAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0129214-B1 METHOD FOR THE PREPARATION OF BENZENAMINES OCCIDENTAL CHEMICAL CORPORATION (US) 1986-10-29 EP disclosed