SCHEMBL10885308

SCHEMBL10885308

O=[PH](O)OP(=O)(O)NCCc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.47
CA2 P00918 2/20 0.47
CA9 Q16790 2/20 0.47
CA1 P00915 1/20 0.47
MMP1 P03956 1/20 0.47
MMP2 P08253 1/20 0.47
MMP3 P08254 1/20 0.47
ANPEP P15144 3/20 0.43
FDPS P14324 2/20 0.43
ERAP2 Q6P179 2/20 0.43
ESR1 P03372 1/20 0.41
YWHAB P31946 1/20 0.41
PDK1 Q15118 1/20 0.41
TSHR P16473 2/20 0.40
S1PR2 O95136 1/20 0.40
S1PR4 O95977 1/20 0.40
S1PR1 P21453 1/20 0.40
S1PR3 Q99500 1/20 0.40
KDM4E B2RXH2 1/20 0.39
ALDH1A1 P00352 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methane SCHEMBL10784198 0.98 CA12 (0.46) CA12CA2CA9CA1MMP1
SCHEMBL11665520 0.84 KMT2A (0.47) CA12CA2CA9CA1ANPEP
SCHEMBL6901813 0.76 CA12 (0.59) CA12CA2CA9CA1MMP1
SCHEMBL19353089 0.75 CA12 (0.47) CA12CA2CA9CA1MMP1
SCHEMBL10884914 0.72
SCHEMBL9622559 0.71 HPGD (0.46) ANPEPFDPSTSHR
SCHEMBL10885596 0.71 KDM4E (0.43) CA12CA2CA9CA1FDPS
Methane SCHEMBL10784376 0.71
Methane SCHEMBL10783755 0.70 KDM4E (0.42) CA12CA2CA9CA1FDPS
SCHEMBL10885238 0.68 MMP2 (0.40) MMP1MMP2S1PR2S1PR4S1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0096932-B1 PROCESS FOR MAKING A LYOPHILIZED PRODUCT FOR USE IN SKELETAL IMAGING Mallinckrodt, Inc. (a Delaware corporation) (US) 1986-11-26 EP claimed
EP-0096932-B1 PROCESS FOR MAKING A LYOPHILIZED PRODUCT FOR USE IN SKELETAL IMAGING Mallinckrodt, Inc. (a Delaware corporation) (US) 1986-11-26 EP disclosed