Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.47 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.47 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | FDPS | P14324 | 2/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19353062 | 0.81 | NPC1 (0.51) | S1PR1S1PR3S1PR2S1PR4L3MBTL1 | |
| SCHEMBL17333279 | 0.80 | TSHR (0.60) | S1PR1S1PR3S1PR2S1PR4L3MBTL1 | |
| SCHEMBL759323 | 0.80 | LMNA (0.53) | L3MBTL1LMNAPKMTSHR | |
| SCHEMBL7377077 | 0.78 | L3MBTL1 (0.51) | S1PR1S1PR3S1PR2S1PR4L3MBTL1 | |
| SCHEMBL7377076 | 0.77 | L3MBTL1 (0.54) | S1PR1S1PR3S1PR2S1PR4L3MBTL1 | |
| SCHEMBL12555208 | 0.77 | RAB9A (0.46) | CA12CA1CA2MMP1MMP2 | |
| SCHEMBL6901813 | 0.76 | CA12 (0.59) | CA12CA1CA2MMP1MMP2 | |
| SCHEMBL16395023 | 0.76 | L3MBTL1 (0.55) | L3MBTL1LMNAPKMNPC1RAB9A | |
| SCHEMBL22322007 | 0.76 | L3MBTL1 (0.49) | S1PR1S1PR3S1PR2S1PR4L3MBTL1 | |
| SCHEMBL10885308 | 0.75 | CA12 (0.47) | CA12CA1CA2MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10383912-B2 | Tunable pH-sensitive linker for controlled drug release | WASHINGTON STATE UNIVERSITY (US) | 2019-08-20 | — | — | US | disclosed |
| US-20170258936-A1 | Tunable pH-Sensitive Linker for Controlled Drug Release | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10383912-B2 | Tunable pH-sensitive linker for controlled drug release | CA6, NSF, CA7 | CA12 6/4885CA1 12/4885CA2 8/4885 |
| US-20170258936-A1 | Tunable pH-Sensitive Linker for Controlled Drug Release | PHGDH, PHPT1, PHYKPL | CA12 76/4885CA1 134/4885CA2 85/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.