SCHEMBL10885332

SCHEMBL10885332

Nc1c(O)cc([N+](=O)[O-])cc1O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.57
GPR35 Q9HC97 4/20 0.57
MEN1 O00255 3/20 0.57
KMT2A Q03164 3/20 0.57
MAPK1 P28482 3/20 0.57
HPGD P15428 2/20 0.57
ALOX15 P16050 2/20 0.57
HSD17B10 Q99714 2/20 0.57
KDM4E B2RXH2 1/20 0.57
TTR P02766 1/20 0.57
CYP1A2 P05177 1/20 0.57
MAPT P10636 1/20 0.57
CYP2C9 P11712 1/20 0.57
ALOX12 P18054 1/20 0.57
RECQL P46063 1/20 0.57
PMP22 Q01453 1/20 0.57
HIF1A Q16665 1/20 0.57
TDP1 Q9NUW8 1/20 0.57
GAA P10253 1/20 0.55
THRB P10828 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5123353 0.89 GAA (0.60) ALDH1A1GPR35MEN1KMT2AMAPK1
SCHEMBL8449685 0.87 ALDH1A1 (0.66) ALDH1A1GPR35MEN1KMT2AMAPK1
SCHEMBL10699626 0.86 ALDH1A1 (0.74) ALDH1A1GPR35MEN1KMT2AMAPK1
SCHEMBL14356236 0.86 ALDH1A1 (0.55) ALDH1A1GPR35MEN1KMT2AMAPK1
SCHEMBL221843 0.86 ALDH1A1 (0.67) ALDH1A1GPR35MEN1KMT2AMAPK1
SCHEMBL754090 0.86 ALDH1A1 (0.53) ALDH1A1GPR35MEN1KMT2AMAPK1
SCHEMBL11291855 0.86 HTT (0.62) ALDH1A1GPR35MEN1KMT2AMAPK1
SCHEMBL9355259 0.81 NT5E (0.60) ALDH1A1GPR35MEN1KMT2AMAPK1
SCHEMBL9958158 0.81 ALDH1A1 (0.44) ALDH1A1GPR35MEN1KMT2AMAPK1
SCHEMBL9743157 0.80 GPR35 (0.75) ALDH1A1GPR35MEN1KMT2AMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0095410-B1 PHOTOGRAPHIC ELEMENT EMPLOYING A SUBSTITUTED SULFONAMIDOPHENOL OR SULFONAMIDONAPHTHOL DYE-RELEASING COMPOUND EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1986-08-27 EP disclosed
EP-0095410-A2 Photographic element employing a substituted sulfonamidophenol or sulfonamidonaphthol dye-releasing compound EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1983-11-30 EP disclosed
US-4407930-A DIFFUSION TRANSFER EASTMAN KODAK COMPANY (US) 1983-10-04 US disclosed