SCHEMBL14356236

SCHEMBL14356236

Cc1cc([N+](=O)[O-])cc(O)c1N

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.55
GPR35 Q9HC97 4/20 0.55
TDP1 Q9NUW8 3/20 0.53
CYP3A4 P08684 3/20 0.53
HTT P42858 3/20 0.48
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
POLB P06746 1/20 0.48
KDM4E B2RXH2 1/20 0.48
TTR P02766 1/20 0.48
CYP1A2 P05177 1/20 0.48
MAPT P10636 1/20 0.48
CYP2C9 P11712 1/20 0.48
HPGD P15428 1/20 0.48
ALOX15 P16050 1/20 0.48
ALOX12 P18054 1/20 0.48
MAPK1 P28482 1/20 0.48
RECQL P46063 1/20 0.48
PMP22 Q01453 1/20 0.48
HIF1A Q16665 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10885332 0.86 ALDH1A1 (0.57) ALDH1A1GPR35TDP1CYP3A4HTT
SCHEMBL3600387 0.86 ALDH1A1 (0.63) ALDH1A1GPR35TDP1CYP3A4HTT
SCHEMBL2119829 0.80 ALDH1A1 (0.62) ALDH1A1GPR35TDP1CYP3A4HTT
SCHEMBL69972 0.80 GPR35 (0.69) ALDH1A1GPR35TDP1CYP3A4HTT
SCHEMBL5123353 0.80 GAA (0.60) ALDH1A1GPR35TDP1CYP3A4HTT
SCHEMBL11112395 0.80 ALDH1A1 (0.58) ALDH1A1GPR35TDP1CYP3A4HTT
SCHEMBL28009106 0.78 GPR35 (0.67) ALDH1A1GPR35TDP1CYP3A4HTT
SCHEMBL8449685 0.78 ALDH1A1 (0.66) ALDH1A1GPR35TDP1CYP3A4HTT
SCHEMBL6672266 0.78 ALDH1A1 (0.63) ALDH1A1GPR35TDP1CYP3A4HTT
SCHEMBL655655 0.77 GPR35 (0.77) ALDH1A1GPR35TDP1CYP3A4HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7301013-B2 Azo compounds CLARIANT FINANCE (BVI) LIMITED (GB) 2007-11-27 US disclosed