Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 6/20 | 0.60 |
| ▸ | LAP3 | P28838 | 1/20 | 0.60 |
| ▸ | PPARG | P37231 | 4/20 | 0.51 |
| ▸ | PPARA | Q07869 | 2/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.50 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10885560 | 0.91 | SLC7A5 (0.53) | LTA4HLAP3PTGS1 | |
| SCHEMBL10886482 | 0.89 | LTA4H (0.48) | LTA4HLAP3PPARGPPARAPTGS1 | |
| SCHEMBL10884575 | 0.86 | SLC15A1 (0.46) | LTA4HLAP3PPARGPPARAPTGS1 | |
| SCHEMBL10887915 | 0.86 | SLC15A1 (0.46) | LTA4HLAP3PPARGPPARAPTGS1 | |
| SCHEMBL1855604 | 0.84 | LTA4H (0.73) | LTA4HLAP3PPARGPPARAFFAR1 | |
| SCHEMBL8413771 | 0.84 | LTA4H (0.73) | LTA4HLAP3PPARGPPARAFFAR1 | |
| SCHEMBL6561218 | 0.84 | LTA4H (0.73) | LTA4HLAP3PPARGPPARAFFAR1 | |
| Hydrochloric Acid SCHEMBL6271718 | 0.83 | LTA4H (0.71) | LTA4HLAP3PPARGPPARAFFAR1 | |
| Hydrochloric Acid SCHEMBL10922580 | 0.83 | LTA4H (0.71) | LTA4HLAP3PPARGPPARAFFAR1 | |
| SCHEMBL16607620 | 0.83 | LTA4H (0.67) | LTA4HLAP3PPARGPPARAFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0071926-B1 | NEW RIBOFURANURONIC ACID DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-10-08 | — | — | EP | claimed |
| EP-0071926-B1 | NEW RIBOFURANURONIC ACID DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-10-08 | — | — | EP | disclosed |
| US-4479942-A | Tetrahydrofurnancarboxylic acid derivatives, processes for preparation thereof and pharmaceutical compositions thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-10-30 | — | — | US | disclosed |
| EP-0071926-A1 | New ribofuranuronic acid derivatives, processes for preparation thereof and pharmaceutical compositions thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-02-16 | — | — | EP | disclosed |