Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10888885 | 0.83 | MEN1 (0.52) | CYP2D6ADRB2ADRB1ADRB3 | |
| SCHEMBL10891570 | 0.81 | ADRB2 (0.64) | CYP2D6ADRB2ADRB1ADRB3 | |
| SCHEMBL10896934 | 0.80 | KDM4E (0.54) | — | |
| Hydrochloric Acid SCHEMBL28047728 | 0.77 | — | — | |
| Levomoprolol SCHEMBL80725 | 0.76 | ADRB2 (0.74) | CYP2D6ADRB2ADRB1ADRB3 | |
| Moprolol SCHEMBL30002163 | 0.76 | ADRB2 (0.74) | CYP2D6ADRB2ADRB1ADRB3 | |
| Moprolol SCHEMBL80724 | 0.76 | ADRB2 (0.74) | CYP2D6ADRB2ADRB1ADRB3 | |
| Moprolol SCHEMBL30910938 | 0.76 | ADRB2 (0.74) | CYP2D6ADRB2ADRB1ADRB3 | |
| SCHEMBL27584406 | 0.75 | CYP2D6 (0.61) | CYP2D6ADRB2ADRB1ADRB3 | |
| Moprolol SCHEMBL9119947 | 0.74 | ADRB2 (0.72) | CYP2D6ADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0110746-B1 | DERIVATIVES OF 3-AMINO-1-PHENOXY-2-PROPANOL, THEIR THERAPEUTICAL USE AND PROCESS FOR THEIR PREPARATION | LABORATOIRE L. LAFON Société anonyme dite: (FR) | 1986-06-11 | — | — | EP | claimed |
| EP-0110746-A1 | Derivatives of 3-amino-1-phenoxy-2-propanol, their therapeutical use and process for their preparation | LABORATOIRE L. LAFON Société anonyme dite: (FR) | 1984-06-13 | — | — | EP | claimed |
| EP-0110746-B1 | DERIVATIVES OF 3-AMINO-1-PHENOXY-2-PROPANOL, THEIR THERAPEUTICAL USE AND PROCESS FOR THEIR PREPARATION | LABORATOIRE L. LAFON Société anonyme dite: (FR) | 1986-06-11 | — | — | EP | disclosed |
| EP-0110746-A1 | Derivatives of 3-amino-1-phenoxy-2-propanol, their therapeutical use and process for their preparation | LABORATOIRE L. LAFON Société anonyme dite: (FR) | 1984-06-13 | — | — | EP | disclosed |