Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 8/20 | 0.42 |
| ▸ | THRA | P10827 | 7/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6237474 | 0.78 | SRD5A2 (0.50) | NR1H4SRD5A2KDM4EALDH1A1GAA | |
| SCHEMBL6239925 | 0.75 | SRD5A2 (0.50) | LMNANR1H4THRBTHRASRD5A2 | |
| SCHEMBL6239365 | 0.74 | SRD5A2 (0.49) | LMNANR1H4THRBTHRASRD5A2 | |
| SCHEMBL4626021 | 0.73 | MEN1 (0.56) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL165470 | 0.72 | EPHX1 (0.51) | LMNAMEN1KMT2ATHRBKDM4E | |
| SCHEMBL9312700 | 0.70 | HPGD (0.64) | MEN1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL5596303 | 0.70 | LMNA (0.64) | LMNADRD2DRD3MEN1KMT2A | |
| SCHEMBL6241535 | 0.69 | CARM1 (0.56) | LMNANR1H4MEN1KMT2ASRD5A2 | |
| SCHEMBL10885684 | 0.69 | ESR1 (0.44) | MEN1KMT2ATHRBTHRASRD5A2 | |
| SCHEMBL163761 | 0.69 | EPHX1 (0.48) | LMNAMEN1KMT2ATHRBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0032286-B1 | METHOD FOR ANALYSIS FOR A MEMBER OF AN IMMUNOLOGICAL PAIR USING A TEST SURFACE; KIT AND TEST SURFACE MATERIAL THEREFOR | SYVA COMPANY (US) | 1986-01-08 | — | — | EP | disclosed |