SCHEMBL10885708

SCHEMBL10885708

C=CC(=O)OCCOc1ccc(Br)c(Br)c1Br

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
THRB P10828 3/20 0.53
TSHR P16473 7/20 0.44
ALDH1A1 P00352 4/20 0.44
TP53 P04637 2/20 0.44
HIF1A Q16665 2/20 0.44
HSD17B10 Q99714 1/20 0.44
CYP3A4 P08684 1/20 0.41
HPGD P15428 1/20 0.38
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
KDM4E B2RXH2 3/20 0.34
GAA P10253 1/20 0.33
FDPS P14324 2/20 0.32
TYMS P04818 1/20 0.32
KMT2A Q03164 1/20 0.31
PTK2B Q14289 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7749061 0.96 ALDH1A1 (0.53) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL11802349 0.93 TSHR (0.51) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL10931059 0.87 THRB (0.55) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL15169906 0.85 THRB (0.49) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL29904785 0.81 THRB (0.51) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL446746 0.81 THRB (0.51) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL447319 0.80 THRB (0.62) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL10882956 0.80 THRB (0.39) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL2034284 0.79 THRB (0.54) THRBTSHRALDH1A1TP53CYP3A4
SCHEMBL39801 0.78 KDM4E (0.56) THRBTSHRALDH1A1HPGDNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0095932-B1 THE USE OF A PARTICULATE POLYMER AS A CARRIER FOR BIOLOGICAL SUBSTANCES AND THE LIKE AND SUCH SUBSTANCES SUPPORTED ON THE CARRIER JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1986-08-06 EP claimed
EP-0095932-A1 The use of a particulate polymer as a carrier for biological substances and the like and such substances supported on the carrier JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1983-12-07 EP claimed
US-3932321-A HOMO- AND COPOLYMERS OF HALOPHENYL ACRYLATES JAPAN SYNTHETIC RUBBER COMPANY LIMITED (JA) 1976-01-13 US claimed
CN-107636038-B Reactive compositions containing mercapto-functional silicon compounds 莫门蒂夫性能材料股份有限公司 2020-09-22 CN disclosed
CN-107132729-B Photosensitive resin composition and application thereof 奇美实业股份有限公司 2020-08-14 CN disclosed
US-10676594-B2 Reactive compositions containing mercapto-functional silicon compound MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2020-06-09 US disclosed
CN-106933033-B Photosensitive resin composition, optical filter and manufacturing method thereof, and liquid crystal display device 奇美实业股份有限公司 2020-03-13 CN disclosed
CN-107015435-B Photosensitive resin composition, color filter and manufacturing method and application thereof 奇美实业股份有限公司 2019-12-13 CN disclosed
EP-3283577-B1 REACTIVE COMPOSITIONS CONTAINING MERCAPTO-FUNCTIONAL SILICON COMPOUND MOMENTIVE PERFORMANCE MAT INC (US) 2019-07-17 EP disclosed
US-20190010309-A1 REACTIVE COMPOSITIONS CONTAINING MERCAPTO-FUNCTIONAL SILICON COMPOUND MOMENTIVE PERFORMANCE MATERIALS INC. 2019-01-10 US disclosed
US-10106671-B2 Reactive compositions containing mercapto-functional silicon compound MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2018-10-23 US disclosed
US-20150042931-A1 BLUE PHOTOSENSITIVE RESIN COMPOSITION FOR COLOR FILTER AND USES THEREOF CHI MEI CORPORATION (TW) 2015-02-12 US disclosed
US-20140346416-A1 PHOTOSENSITIVE RESIN COMPOSITION FOR A COLOR FILTER AND USES THEREOF CHI MEI CORPORATION (TW) 2014-11-27 US disclosed
US-20140343185-A1 RED PHOTOSENSITIVE RESIN COMPOSITION FOR COLOR FILTER AND APPLICATION OF THE SAME CHI MEI CORPORATION (TW) 2014-11-20 US disclosed
US-20130228727-A1 PHOTOSENSITIVE RESIN COMPOSITION AND APPLICATION OF THE SAME CHI MEI CORPORATION (TW) 2013-09-05 US disclosed
US-20130208215-A1 COLOR LIQUID CRYSTAL DISPLAY DEVICE CHI MEI CORPORATION (TW) 2013-08-15 US disclosed
EP-0095932-B1 THE USE OF A PARTICULATE POLYMER AS A CARRIER FOR BIOLOGICAL SUBSTANCES AND THE LIKE AND SUCH SUBSTANCES SUPPORTED ON THE CARRIER JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1986-08-06 EP disclosed
US-4559303-A OF ACRYLIC PHEXOXY ESTER JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1985-12-17 US disclosed
EP-0095932-A1 The use of a particulate polymer as a carrier for biological substances and the like and such substances supported on the carrier JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1983-12-07 EP disclosed
US-3932321-A HOMO- AND COPOLYMERS OF HALOPHENYL ACRYLATES JAPAN SYNTHETIC RUBBER COMPANY LIMITED (JA) 1976-01-13 US disclosed