SCHEMBL447319

SCHEMBL447319

C=CC(=O)OCCOc1ccccc1Br

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.62
RAB9A P51151 2/20 0.57
NPC1 O15118 1/20 0.57
ALDH1A1 P00352 7/20 0.46
KDM4E B2RXH2 5/20 0.46
TSHR P16473 4/20 0.46
TP53 P04637 2/20 0.46
HIF1A Q16665 2/20 0.46
KMT2A Q03164 2/20 0.46
HSD17B10 Q99714 1/20 0.46
MEN1 O00255 1/20 0.46
HTR7 P34969 1/20 0.45
LMNA P02545 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
GRM4 Q14833 1/20 0.43
POLB P06746 1/20 0.43
CYP3A4 P08684 2/20 0.42
PTK2B Q14289 1/20 0.41
CYP1A2 P05177 1/20 0.40
MAPT P10636 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8723335 0.92 THRB (0.53) THRBRAB9ANPC1ALDH1A1KDM4E
SCHEMBL10931059 0.88 THRB (0.55) THRBRAB9ANPC1ALDH1A1KDM4E
SCHEMBL10712230 0.84 THRB (0.66) THRBALDH1A1KDM4ETSHRTP53
SCHEMBL17033941 0.84 THRB (0.66) THRBRAB9ANPC1ALDH1A1KDM4E
SCHEMBL4577955 0.83 THRB (0.64) THRBALDH1A1KDM4ETSHRTP53
SCHEMBL8549379 0.83 THRB (0.64) THRBRAB9ANPC1ALDH1A1KDM4E
SCHEMBL30053278 0.83 THRB (0.64) THRBALDH1A1KDM4ETSHRTP53
SCHEMBL29904785 0.82 THRB (0.51) THRBRAB9ANPC1ALDH1A1KDM4E
SCHEMBL446746 0.82 THRB (0.51) THRBRAB9ANPC1ALDH1A1KDM4E
SCHEMBL7777465 0.81 ALDH1A1 (0.66) THRBALDH1A1KDM4ETSHRTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 157 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4363467-A1 NOVEL DUAL CURE 3D PRINTING RESINS Stratasys, Inc. (US) 2024-05-08 EP claimed
EP-4363223-A1 NOVEL URETHANE ACRYLATE COMPOSITION Stratasys, Inc. (US) 2024-05-08 EP claimed
US-11891469-B2 Urethane acrylate composition STRATASYS, INC. (US) 2024-02-06 US claimed
WO-2023278202-A1 NOVEL URETHANE ACRYLATE COMPOSITION COVESTRO LLC (US) 2023-01-05 WO claimed
WO-2023278201-A1 NOVEL DUAL CURE 3D PRINTING RESINS COVESTRO LLC (US) 2023-01-05 WO claimed
US-20220411563-A1 NOVEL DUAL CURE 3D PRINTING RESINS STRATASYS INC. 2022-12-29 US claimed
US-20220411560-A1 NOVEL URETHANE ACRYLATE COMPOSITION STRATASYS INC. 2022-12-29 US claimed
US-8241755-B2 Polymerizable composition comprising low molecular weight organic component 3M INNOVATIVE PROPERTIES COMPANY (US) 2012-08-14 US claimed
US-20110318538-A1 POLYMERIZABLE COMPOSITION COMPRISING LOW MOLECULAR WEIGHT ORGANIC COMPONENT 3M INNOVATIVE PROPERTIES COMPANY 2011-12-29 US claimed
US-8034421-B2 Polymerizable composition comprising low molecular weight organic component 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-10-11 US claimed
US-8025934-B2 Polymerizable composition comprising low molecular weight organic component 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-09-27 US claimed
US-20100331442-A1 POLYMERIZABLE COMPOSITION COMPRISING LOW MOLECULAR WEIGHT ORGANIC COMPONENT 3M INNOVATIVE PROPERTIES COMPANY 2010-12-30 US claimed
US-20080253148-A1 Polymerizable Composition Comprising Low Molecular Weight Organic Component 3M INNOVATIVE PROPERTIES COMPANY 2008-10-16 US claimed
EP-1861735-A2 POLYMERIZABLE COMPOSITION COMPRISING LOW MOLECULAR WEIGHT ORGANIC COMPONENT 3M Innovative Properties Company (US) 2007-12-05 EP claimed
WO-2006099357-A2 POLYMERIZABLE COMPOSITION COMPRISING LOW MOLECULAR WEIGHT ORGANIC COMPONENT 3M INNOVATIVE PROPERTIES COMPANY (US) 2006-09-21 WO claimed
US-20060204676-A1 Polymerizable composition comprising low molecular weight organic component 3M INNOVATIVE PROPERTIES COMPANY 2006-09-14 US claimed
EP-0735062-B1 ACTINIC-RADIATION-CURABLE COMPOSITION AND LENS SHEET MITSUBISHI RAYON CO (JP) 2002-01-30 EP claimed
US-6206550-B1 BACKLIGHT WITH LENS PORTION MADE FROM A CURABLE COMPOSITION WHICH INCLUDES A BIS(4-(METH)ACRYLOYL-THIOPHENYL) SULFIDE AND (METH)ACRYLATES; HIGH BRIGHTNESS-ENHANCING EFFECT ON LENSES OF PROJECTION TVS AND STEREOSCOPIC PHOTOGRAPHY. MITSUBISHI RAYON COMPANY LTD. (JP) 2001-03-27 US claimed
US-5969867-A ACRYLIC ESTERS MITSUBISHI RAYON COMPANY LTD. (JP) 1999-10-19 US claimed
EP-0735062-A1 ACTINIC-RADIATION-CURABLE COMPOSITION AND LENS SHEET MITSUBISHI RAYON CO., LTD. (JP) 1996-10-02 EP claimed