Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.33 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 5/20 | 0.32 |
| ▸ | PPARD | Q03181 | 5/20 | 0.32 |
| ▸ | PPARA | Q07869 | 5/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.32 |
| ▸ | TLR2 | O60603 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1537455 | 0.91 | CES1 (0.42) | APEX1CES2CES1TSHRALDH1A1 | |
| Acrylonitrile SCHEMBL10699526 | 0.85 | APEX1 (0.35) | APEX1CES2CES1ALDH1A1AKR1B1 | |
| SCHEMBL8089512 | 0.84 | CES1 (0.48) | APEX1CES2CES1TSHRALDH1A1 | |
| SCHEMBL88045 | 0.84 | CES1 (0.48) | APEX1CES2CES1TSHRALDH1A1 | |
| SCHEMBL9167905 | 0.83 | GPR84 (0.50) | APEX1LMNACES2CES1TSHR | |
| Styrene SCHEMBL7110641 | 0.81 | ALOX5 (0.43) | APEX1LMNACES2CES1TSHR | |
| SCHEMBL8586757 | 0.81 | CES1 (0.41) | APEX1CES2CES1TSHRALDH1A1 | |
| SCHEMBL8586760 | 0.81 | CES1 (0.41) | APEX1CES2CES1TSHRALDH1A1 | |
| SCHEMBL12095977 | 0.81 | AKR1B1 (0.52) | APEX1LMNACES2CES1TSHR | |
| SCHEMBL3979241 | 0.81 | CES1 (0.44) | APEX1CES2CES1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1986002371-A1 | LATEXES OF POLYMERS HAVING PENDANT COREACTIVE AND OXAZOLINE GROUPS | THE DOW CHEMICAL COMPANY (US) | 1986-04-24 | — | — | WO | disclosed |
| US-4508869-A | Latexes of polymers having pendant coreactive and oxazoline groups | THE DOW CHEMICAL COMPANY (US) | 1985-04-02 | — | — | US | disclosed |