Styrene

Styrene

SCHEMBL7110641

C=Cc1ccccc1.CCCCC(=CC=C(CC)C(=O)O)C(=O)O

nearest known ligand 0.43

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Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 4/20 0.43
PTGES O14684 3/20 0.43
PPARG P37231 2/20 0.43
LMNA P02545 1/20 0.43
TDP1 Q9NUW8 1/20 0.42
ALDH1A1 P00352 1/20 0.41
TSHR P16473 1/20 0.41
CES2 O00748 3/20 0.41
CES1 P23141 3/20 0.41
APEX1 P27695 1/20 0.38
CYP3A4 P08684 1/20 0.37
CYP2C9 P11712 1/20 0.37
EGFR P00533 1/20 0.37
HDAC3 O15379 1/20 0.37
KDM4E B2RXH2 1/20 0.35
MEN1 O00255 1/20 0.35
RECQL P46063 1/20 0.35
KMT2A Q03164 1/20 0.35
PTGS2 P35354 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL8635873 0.89 AKR1C3 (0.42) ALOX5PTGESPPARGLMNATDP1
Styrene SCHEMBL9725237 0.88 LMNA (0.45) ALOX5PTGESPPARGLMNATDP1
Styrene SCHEMBL27585078 0.85 ALOX5 (0.43) ALOX5PTGESPPARGLMNATDP1
Styrene SCHEMBL10808703 0.84 AKR1C3 (0.46) TDP1ALDH1A1TSHRCYP3A4CYP2C9
SCHEMBL1537455 0.82 CES1 (0.42) PPARGTDP1ALDH1A1TSHRCES2
Styrene SCHEMBL17065130 0.81 LMNA (0.47) ALOX5PTGESPPARGLMNATDP1
Styrene SCHEMBL5270544 0.81 LMNA (0.47) ALOX5PTGESPPARGLMNATDP1
Styrene SCHEMBL258132 0.81 LMNA (0.47) ALOX5PTGESPPARGLMNATDP1
Acrylic Acid SCHEMBL10885709 0.81 APEX1 (0.37) PPARGLMNATDP1ALDH1A1TSHR
Styrene SCHEMBL28040202 0.81 ALDH1A1 (0.50) LMNATDP1ALDH1A1TSHRCES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0758546-B1 Cosmetic composition containing an aqueous dispersion of a nonionic polymer, utilisation and preparation OREAL (FR) 2003-10-29 EP claimed