Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 5/20 | 0.35 |
| ▸ | CA1 | P00915 | 5/20 | 0.35 |
| ▸ | CA2 | P00918 | 5/20 | 0.35 |
| ▸ | CA9 | Q16790 | 5/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | SOD1 | P00441 | 1/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990121 | 0.92 | MAPT (0.54) | ALDH1A1MAPTKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL692667 | 0.84 | MAPT (0.52) | ALDH1A1MAPTKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL10752755 | 0.83 | ALDH1A1 (0.51) | ALDH1A1MAPTKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL11039733 | 0.81 | MAPT (0.44) | ALDH1A1MAPTKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL11297520 | 0.81 | ALDH1A1 (0.51) | ALDH1A1MAPTKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL10884970 | 0.77 | ALDH1A1 (0.61) | ALDH1A1MAPTKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL10651976 | 0.77 | ALDH1A1 (0.47) | ALDH1A1MAPTKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL10607091 | 0.77 | ALDH1A1 (0.50) | ALDH1A1MAPTKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL696836 | 0.76 | ALDH1A1 (0.46) | ALDH1A1MAPTKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL5447378 | 0.76 | MAPT (0.46) | ALDH1A1MAPTKDM4ESMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0072501-B1 | ASYMMETRIC 1:2 CHROMIUM-COMPLEX DYESTUFFS | BAYER AG (DE) | 1986-12-03 | — | — | EP | disclosed |
| US-4234479-A | PRINTING AND DYEING NITROGEN-CONTAINING FIBERS; YELLOW | BAYER AKTIENGESELLSCHAFT (DE) | 1980-11-18 | — | — | US | disclosed |
| US-4029643-A | Chromium containing azo dyes | NIPPON KAYAKU KABUSHIKI KAISHA (JA) | 1977-06-14 | — | — | US | disclosed |