Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 2/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | MPL | P40238 | 4/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.33 |
| ▸ | ATIC | P31939 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10885992 | 0.92 | ALDH1A1 (0.51) | MAPTALDH1A1KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL692667 | 0.90 | MAPT (0.52) | MAPTALDH1A1KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL10752755 | 0.86 | ALDH1A1 (0.51) | MAPTALDH1A1KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL11297520 | 0.83 | ALDH1A1 (0.51) | MAPTALDH1A1KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL11121976 | 0.80 | ALKBH5 (0.50) | MAPTALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL11438946 | 0.80 | MAPT (0.44) | MAPTALDH1A1KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL10651976 | 0.79 | ALDH1A1 (0.47) | MAPTALDH1A1KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL10607091 | 0.79 | ALDH1A1 (0.50) | MAPTALDH1A1KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL696836 | 0.78 | ALDH1A1 (0.46) | MAPTALDH1A1KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL5447378 | 0.78 | MAPT (0.46) | MAPTALDH1A1KDM4ESMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE35359-E | Amine salts of azo pigments based on pyrazolone derivatives | CIBA-GEIGY CORPORATION (US) | 1996-10-22 | — | — | US | disclosed |
| EP-0241413-B1 | AMINE SALTS OF AZO COMPOUNDS | CIBA-GEIGY AG (CH) | 1993-03-03 | — | — | EP | disclosed |
| US-5151505-A | Monoazo dyes containing hydroxypyrazole groups | CIBA-GEIGY CORPORATION (US) | 1992-09-29 | — | — | US | disclosed |
| US-4992495-A | Yellow pigment | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |
| US-4980458-A | Mixed sodium, ammonium and/or calcium salt crystals of laked monoazo disulfonated pyrazolone pigments | CIBA-GEIGY CORPORATION (US) | 1990-12-25 | — | — | US | disclosed |
| EP-0263074-A2 | Mixed crystals of laked azo dyes | CIBA-GEIGY AG (CH) | 1988-04-06 | — | — | EP | disclosed |
| EP-0241413-A2 | Amine salts of azo compounds | CIBA-GEIGY AG (CH) | 1987-10-14 | — | — | EP | disclosed |
| EP-0126405-A1 | Pyrazolone azo dyestuffs | BASF Aktiengesellschaft (DE) | 1984-11-28 | — | — | EP | disclosed |