Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | CACNA1D | Q01668 | 4/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.46 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.46 |
| ▸ | SCN1A | P35498 | 2/20 | 0.46 |
| ▸ | HTR2B | P41595 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.46 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.46 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7890630 | 0.84 | MAPT (0.53) | ALDH1A1CACNA1DADORA3LMNASMN1; SMN2 | |
| SCHEMBL10542632 | 0.79 | CACNA1D (0.55) | ALDH1A1CACNA1DADORA3LMNASMN1; SMN2 | |
| SCHEMBL10619732 | 0.77 | CACNA1D (0.46) | ALDH1A1CACNA1DADORA3LMNASMN1; SMN2 | |
| SCHEMBL8405619 | 0.73 | ADORA3 (0.44) | ALDH1A1CACNA1DADORA3LMNASMN1; SMN2 | |
| SCHEMBL7424140 | 0.71 | ADORA3 (0.76) | ALDH1A1CACNA1DADORA3LMNASMN1; SMN2 | |
| SCHEMBL11821045 | 0.68 | CACNA1D (0.63) | ALDH1A1CACNA1DADORA3LMNASMN1; SMN2 | |
| SCHEMBL11442155 | 0.68 | MAPT (0.50) | ALDH1A1CACNA1DADORA3LMNASMN1; SMN2 | |
| SCHEMBL1672208 | 0.68 | TSHR (0.70) | ALDH1A1CACNA1DADORA3LMNASMN1; SMN2 | |
| SCHEMBL9602040 | 0.67 | CACNA1D (0.57) | ALDH1A1CACNA1DADORA3LMNASMN1; SMN2 | |
| SCHEMBL10885654 | 0.66 | MAPT (0.73) | ALDH1A1CACNA1DADORA3LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0124777-B1 | 1,4-DIHYDROPYRIDINE DERIVATIVES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1986-10-29 | — | — | EP | disclosed |