Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.53 |
| ▸ | CACNA1C | Q13936 | 6/20 | 0.53 |
| ▸ | CACNA1D | Q01668 | 5/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.53 |
| ▸ | TSHR | P16473 | 5/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.53 |
| ▸ | CACNA1F | O60840 | 3/20 | 0.53 |
| ▸ | CACNA1S | Q13698 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.53 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10542632 | 0.86 | CACNA1D (0.55) | MAPTADORA3CACNA1CCACNA1DCYP1A2 | |
| SCHEMBL10619732 | 0.84 | CACNA1D (0.46) | MAPTADORA3CACNA1CCACNA1DCYP1A2 | |
| SCHEMBL10886239 | 0.84 | ALDH1A1 (0.46) | MAPTADORA3CACNA1CCACNA1DCYP1A2 | |
| SCHEMBL8405619 | 0.79 | ADORA3 (0.44) | MAPTADORA3CACNA1CCACNA1DCYP1A2 | |
| SCHEMBL11821045 | 0.74 | CACNA1D (0.63) | MAPTADORA3CACNA1CCACNA1DCYP1A2 | |
| SCHEMBL1672208 | 0.73 | TSHR (0.70) | MAPTADORA3CACNA1CCACNA1DCYP1A2 | |
| SCHEMBL11442155 | 0.73 | MAPT (0.50) | MAPTADORA3CACNA1CCACNA1DCYP1A2 | |
| SCHEMBL9602040 | 0.73 | CACNA1D (0.57) | MAPTADORA3CACNA1CCACNA1DCYP1A2 | |
| SCHEMBL11683170 | 0.72 | TSHR (0.65) | MAPTADORA3CACNA1CCACNA1DCYP1A2 | |
| SCHEMBL12994290 | 0.71 | LMNA (0.66) | MAPTADORA3CACNA1CCACNA1DCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6168806-B1 | Orally administrable nifedipine pellet and process for the preparation thereof | LEE FANG-YU (TW) | 2001-01-02 | — | — | US | disclosed |