SCHEMBL10889083

SCHEMBL10889083

Cc1ccccc1C=NOC(=O)C(Cl)=C(Cl)Cl

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.44
HPGD P15428 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
LMNA P02545 2/20 0.44
HTT P42858 1/20 0.44
SMN1; SMN2 Q16637 3/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
RAB9A P51151 3/20 0.40
NPC1 O15118 2/20 0.40
KDM4E B2RXH2 2/20 0.38
TSHR P16473 1/20 0.38
MAPT P10636 2/20 0.38
CYP1A2 P05177 1/20 0.36
CYP2C19 P33261 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
PLA2G7 Q13093 1/20 0.34
PLK1 P53350 1/20 0.34
MGAM O43451 1/20 0.33
GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13402945 0.83 ALDH1A1 (0.48) ALDH1A1HPGDL3MBTL1LMNAHTT
SCHEMBL10889660 0.82 GRIN2D (0.49) ALDH1A1HPGDLMNASMN1; SMN2MEN1
SCHEMBL13044358 0.79 ALDH1A1 (0.50) ALDH1A1HPGDL3MBTL1LMNAHTT
SCHEMBL28401229 0.79 ALDH1A1 (0.50) ALDH1A1HPGDL3MBTL1LMNAHTT
SCHEMBL10884215 0.78 PLA2G7 (0.57) ALDH1A1HPGDLMNAMEN1KMT2A
SCHEMBL28360400 0.75 ALDH1A1 (0.47) ALDH1A1HPGDL3MBTL1LMNAHTT
SCHEMBL10889088 0.74 ALDH1A1 (0.42) ALDH1A1HPGDL3MBTL1LMNAHTT
SCHEMBL10887029 0.72 CYP1A2 (0.44) ALDH1A1HPGDLMNAHTTSMN1; SMN2
SCHEMBL11098147 0.71 ALDH1A1 (0.45) ALDH1A1HPGDL3MBTL1LMNAHTT
SCHEMBL11098150 0.71 ALDH1A1 (0.45) ALDH1A1HPGDL3MBTL1LMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4581365-A Trichloroacryloyl oxime fungicides NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1986-04-08 US claimed