Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10889100 | 0.78 | SMN1; SMN2 (0.42) | LMNAMAPTKMT2AALDH1A1HTT | |
| SCHEMBL2454952 | 0.77 | TSHR (0.50) | TSHRNOTUMLMNAMAPTKMT2A | |
| SCHEMBL14275065 | 0.76 | HPGD (0.43) | TSHRLMNAMAPTKMT2AALDH1A1 | |
| SCHEMBL8178094 | 0.75 | CES1 (0.43) | TSHRLMNAKMT2ASMN1; SMN2 | |
| SCHEMBL29366012 | 0.74 | LMNA (0.40) | LMNAMAPTKMT2AALDH1A1HTT | |
| SCHEMBL5590841 | 0.74 | SMN1; SMN2 (0.49) | TSHRALDH1A1HTTHSD17B10KDM4E | |
| SCHEMBL9634740 | 0.74 | LMNA (0.41) | TSHRLMNAL3MBTL1CA12CA14 | |
| SCHEMBL19432778 | 0.74 | CYP2D6 (0.35) | TSHRLMNAMAPTKMT2AALDH1A1 | |
| SCHEMBL24721083 | 0.73 | GAA (0.33) | HTTSMN1; SMN2GAAHPGD | |
| SCHEMBL16203504 | 0.73 | LMNA (0.39) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3746151-A1 | EXTRACORPOREAL DEVICE AND MATRIX FOR REMOVING FIBRINOLYTIC PROTEINS FROM BIOLOGICAL FLUIDS, METHODS AND USES THEREOF | PLAS-FREE LTD. (IL) | 2020-12-09 | — | — | EP | disclosed |