Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 13/20 | 0.46 |
| ▸ | CNR2 | P34972 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10893564 | 0.89 | CNR2 (0.49) | KCNH2CNR2MEN1KMT2AGAA | |
| SCHEMBL2881066 | 0.80 | CNR2 (0.63) | CNR2MEN1KMT2AGAAMAPT | |
| SCHEMBL10890941 | 0.77 | TAAR1 (0.46) | KCNH2MAPTHTT | |
| SCHEMBL6565246 | 0.76 | EGFR (0.47) | KCNH2CNR2 | |
| Trimethylammonium SCHEMBL6555079 | 0.76 | CNR2 (0.59) | CNR2MEN1KMT2AMAPT | |
| SCHEMBL6344469 | 0.76 | CNR2 (0.59) | CNR2MEN1KMT2AMAPT | |
| SCHEMBL5536365 | 0.75 | CNR2 (0.44) | KCNH2CNR2MEN1KMT2AGAA | |
| SCHEMBL11328266 | 0.74 | CNR2 (0.46) | CNR2MEN1KMT2AGAAMAPT | |
| Methane SCHEMBL10535102 | 0.74 | CNR2 (0.58) | CNR2MEN1KMT2AMAPT | |
| SCHEMBL28598991 | 0.73 | CNR2 (0.54) | KCNH2CNR2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4596891-A | PHENYL-N,N'-DIETHYLETHYLENE DIAMINES | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1986-06-24 | — | — | US | disclosed |
| US-4286983-A | INCLUDING COMPOUNDS OF THE N-PHENYL-N',N'-DIETHYL ALKYLENEDIAMINE TYPE | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1981-09-01 | — | — | US | disclosed |