Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 3/20 | 0.43 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10889974 | 0.89 | KCNH2 (0.46) | CNR2MEN1KMT2AMAPTGAA | |
| SCHEMBL2881066 | 0.83 | CNR2 (0.63) | CNR2MEN1KMT2AMAPTGAA | |
| SCHEMBL10888104 | 0.80 | MEN1 (0.41) | CNR2MEN1KMT2ALMNANPSR1 | |
| SCHEMBL11141853 | 0.79 | TSHR (0.55) | CNR2MEN1KMT2AMAPTGAA | |
| Trimethylammonium SCHEMBL6555079 | 0.79 | CNR2 (0.59) | CNR2MEN1KMT2AMAPTCNR1 | |
| SCHEMBL6344469 | 0.79 | CNR2 (0.59) | CNR2MEN1KMT2AMAPTCNR1 | |
| SCHEMBL11141925 | 0.77 | ALDH1A1 (0.71) | MEN1KMT2AMAPTGAAPSMD14 | |
| SCHEMBL11328266 | 0.77 | CNR2 (0.46) | CNR2MEN1KMT2AMAPTGAA | |
| Methane SCHEMBL10535102 | 0.77 | CNR2 (0.58) | CNR2MEN1KMT2AMAPTCNR1 | |
| SCHEMBL6555099 | 0.76 | ALDH1A1 (0.38) | CNR2GAAPSMD14ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4596891-A | PHENYL-N,N'-DIETHYLETHYLENE DIAMINES | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1986-06-24 | — | — | US | disclosed |
| US-4286983-A | INCLUDING COMPOUNDS OF THE N-PHENYL-N',N'-DIETHYL ALKYLENEDIAMINE TYPE | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1981-09-01 | — | — | US | disclosed |