Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EBP | Q15125 | 5/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.57 |
| ▸ | ESR1 | P03372 | 7/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.53 |
| ▸ | DHCR7 | Q9UBM7 | 2/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.52 |
| ▸ | DRD3 | P35462 | 2/20 | 0.52 |
| ▸ | HTR6 | P50406 | 2/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10887720 | 0.94 | ALDH1A1 (0.51) | EBPSIGMAR1ESR1ESR2DHCR7 | |
| SCHEMBL11127711 | 0.84 | EBP (0.58) | EBPSIGMAR1ESR1ESR2KCNH2 | |
| SCHEMBL10885901 | 0.78 | EBP (0.57) | EBPSIGMAR1ESR1ESR2KCNH2 | |
| SCHEMBL10888476 | 0.76 | EBP (0.66) | EBPSIGMAR1ESR1ESR2KCNH2 | |
| SCHEMBL10790361 | 0.75 | RAB9A (0.45) | ESR1ESR2CHRM2ADRA2AADORA3 | |
| Guaiactamine SCHEMBL25797 | 0.73 | ALDH1A1 (0.78) | DRD3CYP2D6HTTKDM4EDRD1 | |
| SCHEMBL10890295 | 0.73 | EBP (0.61) | EBPSIGMAR1ESR1ESR2KCNH2 | |
| SCHEMBL10886087 | 0.72 | EBP (0.57) | EBPSIGMAR1ESR1ESR2DHCR7 | |
| SCHEMBL9706125 | 0.72 | EBP (0.72) | EBPSIGMAR1ESR1KCNH2CHRM2 | |
| SCHEMBL10884852 | 0.72 | EBP (0.56) | EBPSIGMAR1ESR1ESR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0115080-B1 | (OMEGA-(DIETHYLAMINO)-ALKOXY)-ALPHA-(ETHYL)-BENZHYDROL DERIVATIVES, THEIR ACID ADDITION SALTS AND QUATERNARY SALTS, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THESE COMPOUNDS | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1986-04-16 | — | — | EP | claimed |
| EP-0115080-A1 | (Omega-(diethylamino)-alkoxy)-alpha-(ethyl)-benzhydrol derivatives, their acid addition salts and quaternary salts, process for their preparation and medicines containing these compounds | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1984-08-08 | — | — | EP | claimed |
| EP-0115080-A1 | (Omega-(diethylamino)-alkoxy)-alpha-(ethyl)-benzhydrol derivatives, their acid addition salts and quaternary salts, process for their preparation and medicines containing these compounds | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1984-08-08 | — | — | EP | disclosed |