Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10890866 | 0.92 | LMNA (0.39) | LMNATSHRMAPK1ALDH1A1MAPT | |
| SCHEMBL11200754 | 0.90 | ALDH1A1 (0.39) | LMNATSHRMAPK1ALDH1A1MAPT | |
| SCHEMBL10899048 | 0.84 | ALDH1A1 (0.40) | LMNAALDH1A1MAPTRECQLPOLB | |
| SCHEMBL9493016 | 0.80 | LMNA (0.50) | LMNATSHRMAPK1ALDH1A1MAPT | |
| SCHEMBL9493012 | 0.80 | LMNA (0.50) | LMNATSHRMAPK1ALDH1A1MAPT | |
| SCHEMBL9493024 | 0.79 | LMNA (0.40) | LMNATSHRMAPK1ALDH1A1MAPT | |
| Phosphoric Acid SCHEMBL11090384 | 0.77 | LMNA (0.49) | LMNATSHRMAPK1ALDH1A1MAPT | |
| SCHEMBL10881231 | 0.77 | LMNA (0.39) | LMNATSHRMAPK1ALDH1A1MAPT | |
| SCHEMBL10899040 | 0.75 | ALDH1A1 (0.41) | LMNAALDH1A1MAPTRECQLPOLB | |
| SCHEMBL9494278 | 0.74 | LMNA (0.52) | LMNATSHRMAPK1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0085275-A1 | Substituted thiazolidinylic esters of mineral acids | CIBA-GEIGY AG (CH) | 1983-08-10 | — | — | EP | claimed |
| US-4582841-A | ANTITUMOR AND -CARCINOGENIC AGENTS | CIBA-GEIGY CORPORATION (US) | 1986-04-15 | — | — | US | disclosed |
| US-4489069-A | ANTITUMOR | CIBA-GEIGY AG (CH) | 1984-12-18 | — | — | US | disclosed |