Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.49 |
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | F10 | P00742 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | PLAT | P00750 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4199012 | 0.87 | CHRM1 (0.37) | LTA4H | |
| SCHEMBL4199016 | 0.87 | CHRM1 (0.37) | LTA4H | |
| SCHEMBL5289989 | 0.80 | LTA4H (0.50) | LTA4HCYP1A2CYP2D6CYP2C19SMN1; SMN2 | |
| SCHEMBL23130390 | 0.76 | KDM1A (0.51) | CYP2C19SMN1; SMN2 | |
| SCHEMBL6224277 | 0.74 | SMN1; SMN2 (0.41) | F2F10PLATPRSS1PRSS2 | |
| SCHEMBL27356338 | 0.73 | CYP1A2 (0.40) | LTA4HF2F10PLATPRSS1 | |
| SCHEMBL11448671 | 0.73 | LTA4H (0.68) | LTA4H | |
| SCHEMBL11969843 | 0.72 | LTA4H (0.42) | LTA4HCYP1A2CYP2D6CYP2C19SMN1; SMN2 | |
| SCHEMBL6364667 | 0.72 | CYP1A2 (0.44) | F2F10PLATPRSS1PRSS2 | |
| SCHEMBL18577477 | 0.72 | POLB (0.69) | LTA4HSLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4596891-A | PHENYL-N,N'-DIETHYLETHYLENE DIAMINES | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1986-06-24 | — | — | US | disclosed |
| US-4286983-A | INCLUDING COMPOUNDS OF THE N-PHENYL-N',N'-DIETHYL ALKYLENEDIAMINE TYPE | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1981-09-01 | — | — | US | disclosed |