Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.52 |
| ▸ | RARB | P10826 | 1/20 | 0.52 |
| ▸ | RARG | P13631 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | RAPGEF3 | O95398 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10719753 | 0.82 | GSK3B (0.43) | MEN1MAPTKMT2AALDH1A1NPC1 | |
| SCHEMBL10970414 | 0.81 | TSHR (0.37) | HDAC1MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL11203708 | 0.79 | CES2 (0.59) | MEN1KMT2ASRD5A2EPHX2CYP1A2 | |
| SCHEMBL23574725 | 0.79 | HDAC1 (0.53) | HDAC1MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL3675035 | 0.76 | ALDH1A1 (0.54) | HDAC1MEN1MAPTKMT2AALDH1A1 | |
| Water SCHEMBL28711864 | 0.76 | SRD5A2 (0.83) | HDAC1MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL22969892 | 0.75 | HDAC1 (0.44) | HDAC1MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL10946728 | 0.75 | SRD5A2 (0.83) | HDAC1MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL1148445 | 0.75 | SRD5A2 (0.83) | HDAC1MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL2853873 | 0.75 | HDAC1 (0.64) | HDAC1MEN1MAPTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4596885-A | Process for the preparation of phenylglyoxylic acid esters | BAYER AKTIENGESELLSCHAFT (DE) | 1986-06-24 | — | — | US | claimed |
| US-4453974-A | TREATMENT OF SEEDS OR SEEDLINGS | CIBA-GEIGY CORPORATION (US) | 1984-06-12 | — | — | US | claimed |
| EP-0041674-B1 | 2-(TRICHLORO-METHYL-PHENYL)-4-HALOGEN-OXAZOLE DERIVATIVES, PROCESS FOR PREPARING THEM AND RADIATION-SENSITIVE COMPOSITIONS CONTAINING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-02-26 | — | — | EP | disclosed |
| US-4371606-A | 2-(Halogenomethyl-phenyl)-4-halogeno-oxaxole derivatives, a process for the preparation thereof, and radiation-sensitive compositions containing these derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-02-01 | — | — | US | disclosed |
| EP-0041674-A2 | 2-(Trichloro-methyl-phenyl)-4-halogen-oxazole derivatives, process for preparing them and radiation-sensitive compositions containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-12-16 | — | — | EP | disclosed |
| US-4228082-A | FUNGICIDES OR CHEMICAL INTERMIDIATES FOR 1,2,4-TRIAZINONE HERBICIDES | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) | 1980-10-14 | — | — | US | disclosed |
| US-4224226-A | FUNGICIDES BY CONDENSING AN ACYL CYANIDE WITH EITHER A TERTIARY ALCOHOL OR AN ALKENE | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) | 1980-09-23 | — | — | US | disclosed |