Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.59 |
| ▸ | CES1 | P23141 | 2/20 | 0.59 |
| ▸ | GSK3B | P49841 | 2/20 | 0.55 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | DHODH | Q02127 | 1/20 | 0.49 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | P4HB | P07237 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10719753 | 0.82 | GSK3B (0.43) | GSK3BSRD5A2CYP1A2MEN1HPGD | |
| SCHEMBL10970414 | 0.81 | TSHR (0.37) | CES2CES1GSK3BDHODHMEN1 | |
| SCHEMBL12045745 | 0.79 | CES2 (0.59) | CES2CES1GSK3BSRD5A2PTPN1 | |
| SCHEMBL10891997 | 0.79 | HDAC1 (0.53) | SRD5A2CYP1A2MEN1KMT2AKIF11 | |
| SCHEMBL10897558 | 0.77 | CES2 (0.65) | CES2SRD5A2MAOBMEN1HPGD | |
| SCHEMBL11335661 | 0.77 | DHODH (0.62) | CES2CES1GSK3BSRD5A2PTPN1 | |
| SCHEMBL11335664 | 0.77 | DHODH (0.62) | CES2CES1GSK3BSRD5A2PTPN1 | |
| SCHEMBL10945003 | 0.77 | CES2 (0.50) | CES2CES1GSK3BSRD5A2PTPN1 | |
| SCHEMBL17303305 | 0.76 | CES2 (0.55) | CES2CES1GSK3BSRD5A2PTPN1 | |
| Water SCHEMBL28138640 | 0.76 | SRD5A2 (0.83) | CES2CES1GSK3BSRD5A2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9630933-B2 | Method for producing 1-H-tetrazole derivative | NIPPON SODA CO., LTD. (JP) | 2017-04-25 | — | — | US | disclosed |
| US-9630933-B2 | Method for producing 1-H-tetrazole derivative | NIPPON SODA CO., LTD. (JP) | 2017-04-25 | — | — | US | disclosed |
| US-20150322021-A1 | METHOD FOR PRODUCING 1-H-TETRAZOLE DERIVATIVE | NIPPON SODA CO., LTD. (JP) | 2015-11-12 | — | — | US | disclosed |
| US-20150322021-A1 | METHOD FOR PRODUCING 1-H-TETRAZOLE DERIVATIVE | NIPPON SODA CO., LTD. (JP) | 2015-11-12 | — | — | US | disclosed |
| US-20150158829-A1 | METHOD FOR PRODUCING AZIDE COMPOUND, AND METHOD FOR PRODUCING 1-H-TETRAZOLE DERIVATIVE | NIPPON SODA CO., LTD. (JP) | 2015-06-11 | — | — | US | disclosed |
| US-20150158829-A1 | METHOD FOR PRODUCING AZIDE COMPOUND, AND METHOD FOR PRODUCING 1-H-TETRAZOLE DERIVATIVE | NIPPON SODA CO., LTD. (JP) | 2015-06-11 | — | — | US | disclosed |
| EP-0093338-A1 | Method for the preparation of cyanohydrine-carboxylic-acid esters | BAYER AG (DE) | 1983-11-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150322021-A1 | METHOD FOR PRODUCING 1-H-TETRAZOLE DERIVATIVE | CBR1, RIF1, CBR3 | CES2 2160/4885CES1 2747/4885GSK3B 1841/4885 |
| US-20150158829-A1 | METHOD FOR PRODUCING AZIDE COMPOUND, AND METHOD FOR PRODUCING 1-H-TETRAZOLE DERIVATIVE | AS3MT, MSMO1, ABL1 | CES2 1018/4885CES1 3326/4885GSK3B 2888/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.