Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10894194 | 0.72 | SERPINE1 (0.36) | SERPINE1TSHRLMNAKMT2AMEN1 | |
| SCHEMBL17774582 | 0.66 | LMNA (0.46) | TSHRLMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL9320508 | 0.62 | ALDH1A1 (0.52) | TSHRLMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL10432144 | 0.62 | DHFR (0.36) | TSHRKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL29406750 | 0.61 | KDM4E (0.48) | TSHRLMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL9320675 | 0.61 | SMN1; SMN2 (0.61) | TSHRLMNAKMT2AALDH1A1KDM4E | |
| SCHEMBL29403021 | 0.61 | SMN1; SMN2 (0.61) | TSHRLMNAKMT2AALDH1A1KDM4E | |
| SCHEMBL17774612 | 0.61 | PRKCI (0.49) | SERPINE1TSHRLMNAKMT2AMEN1 | |
| SCHEMBL17774555 | 0.60 | HTT (0.51) | TSHRLMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL17774564 | 0.60 | GAA (0.53) | TSHRLMNAKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4588810-A | Basic triphendioxazine dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1986-05-13 | — | — | US | disclosed |