Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INSR | P06213 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | FBP1 | P09467 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | MC5R | P33032 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | CCR2 | P41597 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6655466 | 0.85 | HPGD (0.54) | INSRHPGDHSD17B10ALDH1A1ADRA2A | |
| SCHEMBL31314986 | 0.83 | INSR (0.65) | INSRHPGDHSD17B10ALDH1A1ADRA2A | |
| SCHEMBL1506734 | 0.83 | INSR (0.65) | INSRHPGDHSD17B10ALDH1A1ADRA2A | |
| SCHEMBL10894663 | 0.79 | INSR (0.51) | INSRHPGDHSD17B10ALDH1A1ADRA2A | |
| SCHEMBL6635403 | 0.79 | INSR (0.53) | INSRHPGDHSD17B10ALDH1A1ADRA2A | |
| SCHEMBL1222861 | 0.79 | HPGD (0.53) | INSRHPGDHSD17B10ALDH1A1ADRA2A | |
| SCHEMBL1304086 | 0.79 | INSR (0.49) | INSRHPGDHSD17B10ALDH1A1ADRA2A | |
| SCHEMBL1222858 | 0.79 | INSR (0.49) | INSRHPGDHSD17B10ALDH1A1ADRA2A | |
| SCHEMBL19849828 | 0.79 | HPGD (0.49) | INSRHPGDHSD17B10ALDH1A1ADRA2A | |
| SCHEMBL6998648 | 0.79 | INSR (0.49) | INSRHPGDHSD17B10ALDH1A1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4614745-A | Anti-allergic 3-(carboxycarbonyl)amino benzothiopyran-4-one derivatives, compositions, and method of use therefor | CIBA-GEIGY CORPORATION (US) | 1986-09-30 | — | — | US | disclosed |
| EP-0159964-A2 | 3-Substituted thiopyrone | CIBA-GEIGY AG (CH) | 1985-10-30 | — | — | EP | disclosed |